Complexities in the diagnosis of syphilis continue to challenge clinicians. While direct tests
(eg, microscopy or PCR) are helpful in early syphilis, the mainstay of diagnosis remains …

SUMMARY Point-of-care (POC) laboratories that deliver rapid diagnoses of infectious
diseases were invented to balance the centralization of core laboratories. POC laboratories …

2020 European guideline on the management of syphilis Page 1 GUIDELINES 2020 European
guideline on the management of syphilis M. Janier,1,* M. Unemo,2 N. Dupin,3 GS Tiplica,4 M …

Background Syphilis remains a major public health problem in Europe (both in Eastern
Europe since the 1990's and in Western Europe since the re‐emergence of the disease in …

Health economics has been an established feature of the research, policymaking, practice
and management in the delivery of healthcare. However its role is increasing as the cost of …

Objective The aim of this study was to investigate clinical features and outcomes of children
treated for congenital syphilis (CS). Methods Infants born alive in the public sector of São …

Background Mother-to-child transmission of syphilis remains a leading cause of neonatal
death and stillbirth, disproportionally affecting women in low-resource settings where …

Sexually transmitted infections (STIs) impose major health and economic burdens globally.
More than 35 bacterial, viral, and parasitic pathogens have been identified as sexually …

Background Syphilis in pregnancy imposes a significant global health and economic
burden. More than half of cases result in serious adverse events, including infant mortality …

Background. Rapid point-of-care (POC) syphilis tests based on simultaneous detection of
treponemal and nontreponemal antibodies (dual POC tests) offer the opportunity to increase …