Müller glial cells span the entire thickness of the tissue, and ensheath all retinal neurons, in
vertebrate retinae of all species. This morphological relationship is reflected by a multitude …

The retina provides exquisitely sensitive vision that relies on the integrity of a uniquely
vulnerable cell, the photoreceptor (PR). The genetic and mechanistic causes of retinal …

Microglia, the resident immune cells of the brain and retina, are constantly engaged in the
surveillance of their surrounding neural tissue. During embryonic development they infiltrate …

PURPOSE: To investigate whether retinal ganglion cell death in experimental glaucoma and
after axotomy occurs by apoptosis. METHODS: Chronic elevated eye pressure was …

Objective: To determine the extent of preservation in the inner retina in retinitis pigmentosa
(RP). Methods: We analyzed sectioned maculae of 21 postmortem eyes with RP and 19 age …

Human retinal dystrophies and degenerations and light-induced retinal degenerations in
animal models are sharing an important feature: visual cell death by apoptosis. Studying …

Essential polyunsaturated fatty acids (PUFAs) are critical nutritional lipids that must be
obtained from the diet to sustain homeostasis. Omega-3 and-6 PUFAs are key components …

Objective To investigate apoptosis in human age-related macular degeneration (AMD).
Methods Postmortem retinas with AMD and normal retinas were studied by terminal …

Activation of microglia commonly occurs in response to a wide variety of pathological stimuli
including trauma, axotomy, ischemia, and degeneration in the CNS. In the retina, prolonged …

PURPOSE: To investigate the possibility that cell death in retinal detachment may occur by
reactivation of apoptotic programmed cell death mechanisms. METHODS: Unilateral retinal …