Preeclampsia is a common pregnancy complication, affecting 2% to 8% of pregnancies
worldwide, and is an important cause of both maternal and fetal morbidity and mortality …

Aims Pregnancy hypertension-induced endothelial dysfunction associated with impairment
of nitric oxide (NO) bioavailability and hemodynamic derangements is a challenging for …

Chronic obstructive pulmonary disease (COPD) is a major cause of death and a still
incurable disease, comprising emphysema and chronic bronchitis. In addition to airflow …

Previous experiments in animals and humans show that shifts in microbiota and its
metabolites are linked to hypertension. The present study investigates whether doxycycline …

BKCa channels (large-conductance Ca2+-activated K+ channels) play a critical role in
regulating vascular tone and blood pressure. These channels are present in the smooth …

Hypertensive pregnancy has been associated with reduced nitric oxide (NO), bioavailability,
and increased activity of matrix metalloproteinases (MMPs). However, it is unclear if MMPs …

Preeclampsia (PE) is a major cause of perinatal and maternal mortality and morbidity, which
affects 2% to 8% of pregnancies in the world. The aberrant maternal inflammation and …

Surgeries that require general anesthesia occur in 1.5–2% of gestations. Isoflurane is
frequently used because of its lower possibility of affecting fetal growth. Therefore, we …

Volatile anesthetics may cause vascular dysfunction; however, underlying effects are
unclear. The aim of the present study was to investigate whether sevoflurane and isoflurane …

Preeclampsia is a hypertensive disorder that occurs during pregnancy. It is a complex
disease with unknown pathogenesis and the leading cause of fetal and maternal mortality …