[HTML][HTML] An inflammation-centric view of neurological disease: beyond the neuron

SD Skaper, L Facci, M Zusso, P Giusti - Frontiers in cellular …, 2018 - frontiersin.org
Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …

Astrocyte roles in traumatic brain injury

JE Burda, AM Bernstein, MV Sofroniew - Experimental neurology, 2016 - Elsevier
Astrocytes sense changes in neural activity and extracellular space composition. In
response, they exert homeostatic mechanisms critical for maintaining neural circuit function …

Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull–meninges connections

R Cai, C Pan, A Ghasemigharagoz, MI Todorov… - Nature …, 2019 - nature.com
Abstract Analysis of entire transparent rodent bodies after clearing could provide holistic
biological information in health and disease, but reliable imaging and quantification of …

The contribution of astrocytes and microglia to traumatic brain injury

IP Karve, JM Taylor, PJ Crack - British journal of pharmacology, 2016 - Wiley Online Library
Traumatic brain injury (TBI) represents a major cause of death and disability in developed
countries. Brain injuries are highly heterogeneous and can also trigger other neurological …

Sexual dimorphism in the inflammatory response to traumatic brain injury

S Villapol, DJ Loane, MP Burns - Glia, 2017 - Wiley Online Library
The activation of resident microglial cells, alongside the infiltration of peripheral
macrophages, are key neuroinflammatory responses to traumatic brain injury (TBI) that are …

Response of the cerebral vasculature following traumatic brain injury

A Salehi, JH Zhang, A Obenaus - Journal of Cerebral Blood …, 2017 - journals.sagepub.com
The critical role of the vasculature and its repair in neurological disease states is beginning
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …

[HTML][HTML] Emerging roles for the immune system in traumatic brain injury

CA McKee, JR Lukens - Frontiers in immunology, 2016 - frontiersin.org
Traumatic brain injury (TBI) affects an ever-growing population of all ages with long-term
consequences on health and cognition. Many of the issues that TBI patients face are thought …

[HTML][HTML] Pathophysiological responses and roles of astrocytes in traumatic brain injury

S Michinaga, Y Koyama - International journal of molecular sciences, 2021 - mdpi.com
Traumatic brain injury (TBI) is immediate damage caused by a blow to the head resulting
from traffic accidents, falls, and sporting activity, which causes death or serious disabilities in …

[HTML][HTML] Brain–immune interactions and neuroinflammation after traumatic brain injury

V Dinet, KG Petry, J Badaut - Frontiers in neuroscience, 2019 - frontiersin.org
Traumatic brain injury (TBI) is the principal cause of death and disability in children and
young adults. Clinical and preclinical research efforts have been carried out to understand …

Mechanisms of endogenous neuroprotective effects of astrocytes in brain injury

MA Bylicky, GP Mueller, RM Day - Oxidative medicine and …, 2018 - Wiley Online Library
Astrocytes, once believed to serve only as “glue” for the structural support of neurons, have
been demonstrated to serve critical functions for the maintenance and protection of neurons …