Assessing the ecological risks of per‐and polyfluoroalkyl substances: Current state‐of‐the science and a proposed path forward

GT Ankley, P Cureton, RA Hoke… - Environmental …, 2021 - Wiley Online Library
Per‐and poly‐fluoroalkyl substances (PFAS) encompass a large, heterogenous group of
chemicals of potential concern to human health and the environment. Based on information …

[HTML][HTML] Understanding the dynamics of physiological changes, protein expression, and PFAS in wildlife

J Bangma, TC Guillette, PA Bommarito, C Ng… - Environment …, 2022 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) accumulation and elimination in both wildlife
and humans is largely attributed to PFAS interactions with proteins, including but not limited …

Evaluation of developmental toxicity, developmental neurotoxicity, and tissue dose in zebrafish exposed to GenX and other PFAS

S Gaballah, A Swank, JR Sobus… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Per-and polyfluoroalkyl substances (PFAS) are a diverse class of industrial
chemicals with widespread environmental occurrence. Exposure to long-chain PFAS is …

Behavioural effects and bioconcentration of per-and polyfluoroalkyl substances (PFASs) in zebrafish (Danio rerio) embryos

F Menger, J Pohl, L Ahrens, G Carlsson, S Örn - Chemosphere, 2020 - Elsevier
Per-and polyfluoroalkyl substances (PFASs) are contaminants of emerging concern (CECs)
that cause concern regarding their environmental impact and risk to human health. In this …

Realistic polyethylene terephthalate nanoplastics and the size-and surface coating-dependent toxicological impacts on zebrafish embryos

Y Ji, C Wang, Y Wang, L Fu, M Man… - Environmental Science …, 2020 - pubs.rsc.org
Nanoplastics (NPs) as pollutants in aquatic environments and as a public health issue due
to their accumulation in food chains are of increasing concern. However, previous studies …

[HTML][HTML] Assessment of unique behavioral, morphological, and molecular alterations in the comparative developmental toxicity profiles of PFOA, PFHxA, and PFBA …

O Wasel, KM Thompson, JL Freeman - Environment international, 2022 - Elsevier
Perfluoroalkyl substances (PFAS) are a class of synthetic chemicals that are persistent in the
environment. Due to adverse health outcomes associated with longer chain PFAS, shorter …

Comparative toxicometabolomics of perfluorooctanoic acid (PFOA) and next-generation perfluoroalkyl substances

KY Gebreab, MNH Eeza, T Bai, Z Zuberi, J Matysik… - Environmental …, 2020 - Elsevier
Owing to environmental health concerns, a number of per-and polyfluoroalkyl substances
(PFAS) have been phased-out, and increasingly replaced by various chemical analogs …

Comparative toxicokinetics and toxicity of PFOA and its replacement GenX in the early stages of zebrafish

K Satbhai, C Vogs, J Crago - Chemosphere, 2022 - Elsevier
Per and poly-fluoroalkyl substances (PFAS) are receiving attention due to their persistence,
and potential adverse effects on environmental and human health. Efforts to reduce long …

Application of a framework for grouping and mixtures toxicity assessment of PFAS: A closer examination of dose-additivity approaches

PE Goodrum, JK Anderson, AL Luz… - Toxicological …, 2021 - academic.oup.com
Environmental occurrence and biomonitoring data for per-and polyfluoroalkyl substances
(PFAS) demonstrate that humans are exposed to mixtures of PFAS. This article presents a …

[HTML][HTML] Internal relative potency factors based on immunotoxicity for the risk assessment of mixtures of per-and polyfluoroalkyl substances (PFAS) in human …

W Bil, V Ehrlich, G Chen, R Vandebriel… - Environment …, 2023 - Elsevier
Relative potency factors (RPFs) for per-and polyfluoroalkyl substances (PFAS) have
previously been derived based on liver effects in rodents for the purpose of performing …