Oxidative crosslinking of peptides and proteins: Mechanisms of formation, detection, characterization and quantification
E Fuentes-Lemus, P Hägglund, C López-Alarcón… - Molecules, 2021 - mdpi.com
Covalent crosslinks within or between proteins play a key role in determining the structure
and function of proteins. Some of these are formed intentionally by either enzymatic or …
and function of proteins. Some of these are formed intentionally by either enzymatic or …
Keeping α-synuclein at bay: A more active role of molecular chaperones in preventing mitochondrial interactions and transition to pathological states?
EE Aspholm, I Matečko-Burmann, BM Burmann - Life, 2020 - mdpi.com
The property of molecular chaperones to dissolve protein aggregates of Parkinson-related α-
synuclein has been known for some time. Recent findings point to an even more active role …
synuclein has been known for some time. Recent findings point to an even more active role …
Structural basis for dityrosine-mediated inhibition of α-synuclein fibrillization
C Sahin, EC Østerlund, N Österlund… - Journal of the …, 2022 - ACS Publications
α-Synuclein (α-Syn) is an intrinsically disordered protein which self-assembles into highly
organized β-sheet structures that accumulate in plaques in brains of Parkinson's disease …
organized β-sheet structures that accumulate in plaques in brains of Parkinson's disease …
Effects of synthetic short cationic antimicrobial peptides on the catalytic activity of myeloperoxidase, reducing its oxidative capacity
TV Vakhrusheva, AV Sokolov, GD Moroz, VA Kostevich… - Antioxidants, 2022 - mdpi.com
Cationic antimicrobial peptides (CAMPs) have gained attention as promising antimicrobial
therapeutics causing lower or no bacterial resistance. Considerable achievements have …
therapeutics causing lower or no bacterial resistance. Considerable achievements have …
Enfermedad de Parkinson: Modificaciones Oxidativas y su Rol en la Toxicidad de α-Sinucleína
E Giménez - 2022 - sedici.unlp.edu.ar
La Enfermedad de Parkinson (EP) se incluye dentro de un grupo de patologías
neurodegenerativas conocidas como Sinucleopatías, cuya principal característica es la …
neurodegenerativas conocidas como Sinucleopatías, cuya principal característica es la …
Multimodal methods to study protein aggregation and fibrillation
This chapter presents a selection of multimodal (combined) methods for the integral
investigation of different proteins/peptides and their aggregation or fibrillation process in …
investigation of different proteins/peptides and their aggregation or fibrillation process in …