The host immune response in respiratory virus infection: balancing virus clearance and immunopathology

AH Newton, A Cardani, TJ Braciale - Seminars in immunopathology, 2016 - Springer
The respiratory tract is constantly exposed to the external environment, and therefore, must
be equipped to respond to and eliminate pathogens. Viral clearance and resolution of …

Respiratory syncytial virus—a comprehensive review

AT Borchers, C Chang, ME Gershwin… - Clinical reviews in allergy …, 2013 - Springer
Respiratory syncytial virus (RSV) is amongst the most important pathogenic infections of
childhood and is associated with significant morbidity and mortality. Although there have …

Vitamin D decreases respiratory syncytial virus induction of NF-κB–linked chemokines and cytokines in airway epithelium while maintaining the antiviral state

S Hansdottir, MM Monick, N Lovan… - The journal of …, 2010 - journals.aai.org
Epidemiological studies suggest that low vitamin D levels may increase the risk or severity of
respiratory viral infections. In this study, we examined the effect of vitamin D on respiratory …

Bronchiolitis

RL Smyth, PJM Openshaw - The lancet, 2006 - thelancet.com
Bronchiolitis is a distressing, potentially life-threatening respiratory condition that affects
young babies. Around 2–3% of all infants younger than 1 year are admitted to hospital with …

[HTML][HTML] IL-17–induced pulmonary pathogenesis during respiratory viral infection and exacerbation of allergic disease

S Mukherjee, DM Lindell, AA Berlin, SB Morris… - The American journal of …, 2011 - Elsevier
Severe respiratory syncytial virus (RSV) infections are characterized by airway epithelial cell
damage, mucus hypersecretion, and Th2 cytokine production. Less is known about the role …

Respiratory syncytial virus activates innate immunity through Toll-like receptor 2

MR Murawski, GN Bowen, AM Cerny… - Journal of …, 2009 - Am Soc Microbiol
Respiratory syncytial virus (RSV) is a common cause of infection that is associated with a
range of respiratory illnesses, from common cold-like symptoms to serious lower respiratory …

Immune responses and disease enhancement during respiratory syncytial virus infection

PJM Openshaw, JS Tregoning - Clinical microbiology reviews, 2005 - Am Soc Microbiol
Respiratory syncytial virus (RSV) is one of the commonest and most troublesome viruses of
infancy. It causes most cases of bronchiolitis, which is associated with wheezing in later …

Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression

BD Rudd, E Burstein, CS Duckett, X Li… - Journal of …, 2005 - Am Soc Microbiol
Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection in
young infants worldwide. Previous studies have reported that the induction of interleukin …

Chemokines and their receptors in the pathogenesis of allergic asthma: progress and perspective

LR Bisset, P Schmid-Grendelmeier - Current opinion in pulmonary …, 2005 - journals.lww.com
The critical influence of chemokine biology on the outcome of allergic asthma continues to
be highlighted in recent reports describing novel mechanisms by which eosinophils are …

Contribution of cytokines to tissue damage during human respiratory syncytial virus infection

K Bohmwald, NMS Gálvez… - Frontiers in …, 2019 - frontiersin.org
The human respiratory syncytial virus (hRSV) remains one of the leading pathogens causing
acute respiratory tract infections (ARTIs) in children younger than 2 years old, worldwide …