[HTML][HTML] Advances in antibody phage display technology
Phage display technology can be used for the discovery of antibodies for research,
diagnostic, and therapeutic purposes. In this review, we present and discuss key parameters …
diagnostic, and therapeutic purposes. In this review, we present and discuss key parameters …
Putting precision and elegance in enzyme immobilisation with bio-orthogonal chemistry
X Pei, Z Luo, L Qiao, Q Xiao, P Zhang… - Chemical Society …, 2022 - pubs.rsc.org
The covalent immobilisation of enzymes generally involves the use of highly reactive
crosslinkers, such as glutaraldehyde, to couple enzyme molecules to each other or to …
crosslinkers, such as glutaraldehyde, to couple enzyme molecules to each other or to …
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies
Study of monogenic mitochondrial cardiomyopathies may yield insights into mitochondrial
roles in cardiac development and disease. Here, we combined patient-derived and …
roles in cardiac development and disease. Here, we combined patient-derived and …
Ribosome profiling reveals pervasive translation outside of annotated protein-coding genes
Ribosome profiling suggests that ribosomes occupy many regions of the transcriptome
thought to be noncoding, including 5′ UTRs and long noncoding RNAs (lncRNAs) …
thought to be noncoding, including 5′ UTRs and long noncoding RNAs (lncRNAs) …
Site-specific biotinylation of purified proteins using BirA
M Fairhead, M Howarth - Site-Specific Protein Labeling: Methods and …, 2015 - Springer
The binding between biotin and streptavidin or avidin is one of the strongest known non-
covalent biological interactions. The (strept) avidin-biotin interaction has been widely used …
covalent biological interactions. The (strept) avidin-biotin interaction has been widely used …
Design of biologically active binary protein 2D materials
Ordered two-dimensional arrays such as S-layers, and designed analogues,–have intrigued
bioengineers,, but with the exception of a single lattice formed with flexible linkers, they are …
bioengineers,, but with the exception of a single lattice formed with flexible linkers, they are …
Streptavidin–biotin technology: improvements and innovations in chemical and biological applications
Streptavidin and its homologs (together referred to as streptavidin) are widely used in
molecular science owing to their highly selective and stable interaction with biotin. Other …
molecular science owing to their highly selective and stable interaction with biotin. Other …
The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
Regulatory T cells (Treg cells) are required for peripheral tolerance. Evidence indicates that
Treg cells can adopt specialized differentiation programs in the periphery that are controlled …
Treg cells can adopt specialized differentiation programs in the periphery that are controlled …
Transcription factor Foxp3 and its protein partners form a complex regulatory network
The transcription factor Foxp3 is indispensible for the differentiation and function of
regulatory T cells (Treg cells). To gain insights into the molecular mechanisms of Foxp3 …
regulatory T cells (Treg cells). To gain insights into the molecular mechanisms of Foxp3 …
[HTML][HTML] A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs
Summary c-Myc (Myc) is an important transcriptional regulator in embryonic stem (ES) cells,
somatic cell reprogramming, and cancer. Here, we identify a Myc-centered regulatory …
somatic cell reprogramming, and cancer. Here, we identify a Myc-centered regulatory …