Improved MSC minimal criteria to maximize patient safety: a call to embrace tissue factor and hemocompatibility assessment of MSC products

G Moll, JA Ankrum, SD Olson… - Stem cells translational …, 2022 - academic.oup.com
The number of mesenchymal stromal/stem cell (MSC) therapeutics and types of clinical
applications have greatly diversified during the past decade, including rapid growth of poorly …

International stem cell tourism: a critical literature review and evidence-based recommendations

S Lyons, S Salgaonkar, GT Flaherty - International Health, 2022 - academic.oup.com
Stem cell tourism is an emerging area of medical tourism activity. Frustrated by the slow
translation of stem cell research into clinical practice, patients with debilitating conditions …

[HTML][HTML] International Society for Cell & Gene Therapy Position Paper: Key considerations to support evidence-based cell and gene therapies and oppose marketing of …

L Ikonomou, N Cuende, M Forte, BJ Grilley, AD Levine… - Cytotherapy, 2023 - Elsevier
The field of regenerative medicine, including cellular immunotherapies, is on a remarkable
growth trajectory. Dozens of cell-, tissue-and gene-based products have received marketing …

Unproven cell interventions in Poland and the exploitation of European Union law on advanced therapy medicinal products

J Dulak, M Pecyna - Stem Cell Reports, 2023 - cell.com
The global threat of unproven" stem cell therapies" develops despite the repeated
statements of scientific organizations and regulatory agencies warning about the improper …

Time to Total Knee Arthroplasty (TKA) Post Intra-Articular Injection

MG Gesheff, DA Scalzitti, SS Bains, J Dubin… - Journal of Clinical …, 2024 - mdpi.com
Background: Disease-modifying treatments are not currently developed to target the
underlying causes of knee osteoarthritis (KOA). Corticosteroids (CS), hyaluronic acid (HA) …

Remuneration of donors for cell and gene therapies: an update on the principles and perspective of the World Marrow Donor Association

L Hamad, SM Ahmed, E van Eerden… - Bone Marrow …, 2024 - nature.com
The cell and gene therapy (CGT) sector has witnessed significant advancement over the
past decade, the inception of advanced therapy medicinal products (ATMPs) being one of …

Safety and efficacy claims made by US businesses marketing purported stem cell treatments and exosome therapies

L Turner, JR Martinez Jr, S Najjar… - Regenerative …, 2023 - Taylor & Francis
Aim: Examining websites of US businesses engaged in direct-to-consumer advertising of
putative stem cell treatments and exosome therapies, this study investigated the marketing …

Perspective: Why and how ubiquitously distributed, vascular-associated, pluripotent stem cells in the adult body (vaPS Cells) are the next generation of medicine

EU Alt, C Schmitz, X Bai - Cells, 2021 - mdpi.com
A certain cell type can be isolated from different organs in the adult body that can
differentiate into ectoderm, mesoderm, and endoderm, providing significant support for the …

Stem cell-based combinatorial therapies for spinal cord injury: a narrative review of current research and future directions

N Aderinto, MO Abdulbasit… - Annals of Medicine and …, 2023 - journals.lww.com
Spinal cord injury (SCI) is a devastating condition that can result in lifelong disability.
Despite significant progress in SCI research, current treatments only offer limited functional …

A WHO remit to improve global standards for medical products of human origin

E McGrath, MR Herson, MJ Kuehnert… - Bulletin of the World …, 2024 - pmc.ncbi.nlm.nih.gov
In recent decades, considerable advances have been made in assuring the safety of blood
transfusion and organ transplantation. However, with the increasing movement of medical …