Breast cancer in Asia: incidence, mortality, early detection, mammography programs, and risk-based screening initiatives

YX Lim, ZL Lim, PJ Ho, J Li - Cancers, 2022 - mdpi.com
Simple Summary Nearly all breast cancer patients survive for more than five years when the
tumor is found early and in the localized stage. Regular clinical breast examinations …

Proactive breast cancer risk assessment in primary care: a review based on the principles of screening

JA Usher-Smith, S Hindmarch, DP French… - British Journal of …, 2023 - nature.com
In the UK, the National Institute for Health and Care Excellence (NICE) recommends that
women at moderate or high risk of breast cancer be offered risk-reducing medication and …

Whole-exome sequencing study of familial nasopharyngeal carcinoma and its implication for identifying high-risk individuals

TM Wang, YQ He, WQ Xue, JB Zhang… - JNCI: Journal of the …, 2022 - academic.oup.com
Background Nasopharyngeal carcinoma (NPC) is closely associated with genetic factors
and Epstein-Barr virus infection, showing strong familial aggregation. Individuals with a …

[HTML][HTML] Breast cancer risk stratification using genetic and non-genetic risk assessment tools for 246,142 women in the UK Biobank

PJ Ho, EH Lim, M Hartman, FY Wong, J Li - Genetics in Medicine, 2023 - Elsevier
Purpose The benefit of using individual risk prediction tools to identify high-risk individuals
for breast cancer (BC) screening is uncertain, despite the personalized approach of risk …

Global burden of female breast cancer and its association with socioeconomic development status, 1990–2044

J Zhang, Y Lu, N Zhang, Z Yu, H Li, R He… - Cancer …, 2023 - Wiley Online Library
Background Breast cancer is a widespread disease in women worldwide. Aim We aimed to
explore the global epidemiological trends of female breast cancer (FBC) between 1990 and …

Functions and mechanisms of RNA m6A regulators in breast cancer

Y Yang, F Gao, L Ren, N Ren… - … Journal of Oncology, 2024 - spandidos-publications.com
Breast cancer (BC) is a major malignant tumor in females and the incidence rate of BC has
increased worldwide in recent years. N6-methyladenosine (m6A) is a methylation …

Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study

PJ Ho, IBH Tan, DQ Chong, CC Khor, JM Yuan… - Elife, 2023 - elifesciences.org
Background: To evaluate the utility of polygenic risk scores (PRSs) in identifying high-risk
individuals, different publicly available PRSs for breast (n= 85), prostate (n= 37), colorectal …

[HTML][HTML] The polygenic risk score in the breast cancer treatment

F Anaclerio, L Pilenzi, M Minelli… - Journal of …, 2024 - oaepublish.com
Breast cancer (BC) remains the most common cause of death in women worldwide, but
advances in science have allowed earlier diagnosis and more comprehensive treatment …

Will Absolute Risk Estimation for Time to Next Screen Work for an Asian Mammography Screening Population?

PJ Ho, EH Lim, NKB Mohamed Ri, M Hartman… - Cancers, 2023 - mdpi.com
Simple Summary Personalized breast cancer screening has the potential to improve the
accuracy and effectiveness of breast cancer screening by tailoring the screening protocol to …

What do women want to see in a personalized breast cancer risk report? A qualitative study of Asian women of two countries

F Aldila, FN Fj, J Audrienna, LL Sj, S Tang… - Journal of Community …, 2024 - Springer
A breast cancer risk assessment tool for Asian populations, incorporating Polygenic Risk
Score and Gail Model algorithm, has been established and validated. However, effective …