Marine biofilms: diversity, interactions and biofouling

PY Qian, A Cheng, R Wang, R Zhang - Nature Reviews Microbiology, 2022 - nature.com
Marine biofilms are ubiquitous in the marine environment. These complex microbial
communities rapidly respond to environmental changes and encompass hugely diverse …

Understanding the impacts of bacteriophage viruses: from laboratory evolution to natural ecosystems

B Koskella, CA Hernandez… - Annual Review of …, 2022 - annualreviews.org
Viruses of bacteria (bacteriophages or phage) have broad effects on bacterial ecology and
evolution in nature that mediate microbial interactions, shape bacterial diversity, and …

Viruses interact with hosts that span distantly related microbial domains in dense hydrothermal mats

Y Hwang, S Roux, C Coclet, SJE Krause… - Nature Microbiology, 2023 - nature.com
Many microbes in nature reside in dense, metabolically interdependent communities. We
investigated the nature and extent of microbe-virus interactions in relation to microbial …

Developing phage therapy that overcomes the evolution of bacterial resistance

A Oromí-Bosch, JD Antani… - Annual Review of Virology, 2023 - annualreviews.org
The global rise of antibiotic resistance in bacterial pathogens and the waning efficacy of
antibiotics urge consideration of alternative antimicrobial strategies. Phage therapy is a …

Phage predation accelerates the spread of plasmid-encoded antibiotic resistance

C Ruan, J Ramoneda, A Kan, TJ Rudge… - Nature …, 2024 - nature.com
Phage predation is generally assumed to reduce microbial proliferation while not
contributing to the spread of antibiotic resistance. However, this assumption does not …

A retrospective, observational study of 12 cases of expanded-access customized phage therapy: production, characteristics, and clinical outcomes

SI Green, JR Clark, HH Santos… - Clinical Infectious …, 2023 - academic.oup.com
Background Antimicrobial resistance (AMR) is undermining modern medicine, a problem
compounded by bacterial adaptation to antibiotic pressures. Phages are viruses that infect …

Biological foundations of successful bacteriophage therapy

C Venturini, A Petrovic Fabijan… - EMBO Molecular …, 2022 - embopress.org
Bacteriophages (phages) are selective viral predators of bacteria. Abundant and ubiquitous
in nature, phages can be used to treat bacterial infections (phage therapy), including …

Anaerobic methanotroph 'Candidatus Methanoperedens nitroreducens' has a pleomorphic life cycle

SJ McIlroy, AO Leu, X Zhang, R Newell… - Nature …, 2023 - nature.com
Abstract 'Candidatus Methanoperedens' are anaerobic methanotrophic (ANME) archaea
with global importance to methane cycling. Here meta-omics and fluorescence in situ …

Multispecies biofilm architecture determines bacterial exposure to phages

JB Winans, BR Wucher, CD Nadell - PLoS biology, 2022 - journals.plos.org
Numerous ecological interactions among microbes—for example, competition for space and
resources, or interaction among phages and their bacterial hosts—are likely to occur …

Enhanced bacterium–phage symbiosis in attached microbial aggregates on a membrane surface facing elevated hydraulic stress

Y Tan, P Yu, D Huang, MM Yuan, Z Yu… - Environmental …, 2023 - ACS Publications
Phages are increasingly recognized for their importance in microbial aggregates, including
their influence on microbial ecosystem services and biotechnology applications. However …