The pursuit to discover the fundamental biology and mechanisms of aging within the context
of the physical and social environment is critical to designing interventions to prevent and …

Genome-wide association studies (GWAS) have revolutionised the discovery of genes for
common traits and diseases, including obesity-related traits. In less then four years time, 52 …

Conducting genomic research in diverse populations has led to numerous advances in our
understanding of human history, biology, and health disparities, in addition to discoveries of …

Genome-wide association studies (GWAS) have identified 36 loci associated with body
mass index (BMI), predominantly in populations of European ancestry. We conducted a …

Coronary heart disease (CHD) is the leading cause of mortality in African Americans. To
identify common genetic polymorphisms associated with CHD and its risk factors (LDL-and …

Ten years after the Human Genome Project's completion the life sciences stand in a moment
of uncertainty, transition, and contestation. The postgenomic era has seen rapid shifts in …

In recent years, we've developed a much better grasp of the biological and other factors
associated with the development of obesity. Reflecting our evolving understanding of …

Obesity rates have escalated to the point of a global pandemic with varying prevalence
across ethnic groups. These differences are partially explained by lifestyle factors in addition …

Context Second-generation antipsychotics (SGAs) are increasingly used in the treatment of
many psychotic and nonpsychotic disorders. Unfortunately, SGAs are often associated with …

Obesity is an important factor contributing to the global burden of morbidity and mortality. By
identifying obesity susceptibility genes, scientists aim to elucidate some of its aetiology …