C H Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals

J Yamaguchi, AD Yamaguchi… - Angewandte Chemie …, 2012 - Wiley Online Library
The direct functionalization of C H bonds in organic compounds has recently emerged as a
powerful and ideal method for the formation of carbon–carbon and carbon–heteroatom …

Aryl− aryl bond formation by transition-metal-catalyzed direct arylation

D Alberico, ME Scott, M Lautens - Chemical reviews, 2007 - ACS Publications
The biaryl structural motif is a predominant feature in many pharmaceutically relevant and
biologically active compounds. As a result, for over a century1 organic chemists have sought …

Funktionalisierung von C‐H‐Bindungen: neue Synthesemethoden für Naturstoffe und Pharmazeutika

J Yamaguchi, AD Yamaguchi, K Itami - Angewandte Chemie, 2012 - Wiley Online Library
Die direkte Funktionalisierung von C‐H‐Bindungen in organischen Molekülen hat sich in
jüngster Zeit zu einer wirksamen und idealen Methode entwickelt, mit der Kohlenstoff …

The chemistry of recently isolated naturally occurring quinazolinone alkaloids

SB Mhaske, NP Argade - Tetrahedron, 2006 - Elsevier
The present review portrays a concise account of the isolation, bioactivity, and synthesis of
bioactive quinazolinone-based natural products for the period 1983–2005 and the recent …

Synthesis of quinazolinones and quinazolines

DJ Connolly, D Cusack, TP O'Sullivan, PJ Guiry - Tetrahedron, 2005 - Elsevier
Conclusions Given the advances in synthetic methodology and technology in recent years
and the continued interest in the quinazoline skeleton in medicinal chemistry and drug …

Recent advances in the synthesis of (hetero) aryl-substituted heteroarenes via transition metal-catalysed direct (hetero) arylation of heteroarene C–H bonds with aryl …

F Bellina, R Rossi - Tetrahedron, 2009 - Elsevier
(Hetero) aryl groups directly connected by single Csp2–Csp2 bonds to heteroaryl moieties
are present as core structures in many biologically active compounds, 1 naturally-occurring …

Quinoline, quinazoline and acridone alkaloids

JP Michael - Natural product reports, 2007 - pubs.rsc.org
Covering: July 2004 to June 2005. Previous review: Nat. Prod. Rep., 2005, 22, 627 This
review covers the isolation, structure determination, synthesis and biological activity of …

Simple indole alkaloids and those with a nonrearranged monoterpenoid unit

T Kawasaki, K Higuchi - Natural product reports, 2005 - pubs.rsc.org
Simple indole alkaloids and those with a nonrearranged monoterpenoid unit - Natural Product
Reports (RSC Publishing) DOI:10.1039/B502162F Royal Society of Chemistry View PDF …

Recent progress in coupling of two heteroarenes

D Zhao, J You, C Hu - Chemistry–A European Journal, 2011 - Wiley Online Library
The biheteroaryl structural motif is prevalent in polymers, advanced materials, liquid crystals,
ligands, molecules of medicinal interest, and natural products. Many types of synthetic …

α-Amination of nitrogen heterocycles: Ring-fused aminals

C Zhang, CK De, R Mal, D Seidel - Journal of the American …, 2008 - ACS Publications
α-Amination of Nitrogen Heterocycles: Ring-Fused Aminals | Journal of the American
Chemical Society ACS ACS Publications C&EN CAS Find my institution Log In Journal of the …