Insights into the interaction between influenza virus and pneumococcus

JA McCullers - Clinical microbiology reviews, 2006 - Am Soc Microbiol
Bacterial infections following influenza are an important cause of morbidity and mortality
worldwide. Based on the historical importance of pneumonia as a cause of death during …

Targeting the NF-κB pathway in asthma and chronic obstructive pulmonary disease

MR Edwards, NW Bartlett, D Clarke, M Birrell… - Pharmacology & …, 2009 - Elsevier
Asthma and chronic obstructive pulmonary disease are inflammatory lung disorders
responsible for significant morbidity and mortality worldwide. While the importance of …

IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after influenza infection

KF van der Sluijs, LJR van Elden, M Nijhuis… - The Journal of …, 2004 - journals.aai.org
Secondary pneumococcal pneumonia is a serious complication during and shortly after
influenza infection. We established a mouse model to study postinfluenza pneumococcal …

Streptococcus pneumoniae secretes hydrogen peroxide leading to DNA damage and apoptosis in lung cells

P Rai, M Parrish, IJJ Tay, N Li… - Proceedings of the …, 2015 - National Acad Sciences
Streptococcus pneumoniae is a leading cause of pneumonia and one of the most common
causes of death globally. The impact of S. pneumoniae on host molecular processes that …

Alveolar macrophage apoptosis contributes to pneumococcal clearance in a resolving model of pulmonary infection

DH Dockrell, HM Marriott, LR Prince… - The Journal of …, 2003 - journals.aai.org
The role of alveolar macrophages (AM) in host defense against pulmonary infection has
been difficult to establish using in vivo models. This may reflect a reliance on models of …

Human neutrophils kill Streptococcus pneumoniae via serine proteases

AJ Standish, JN Weiser - The Journal of Immunology, 2009 - journals.aai.org
Neutrophils, or polymorphonuclear leukocytes, comprise a crucial component of innate
immunity, controlling bacterial and fungal infection through a combination of both oxidative …

Herpesvirus‐bacteria synergistic interaction in periodontitis

C Chen, P Feng, J Slots - Periodontology 2000, 2020 - Wiley Online Library
The etiopathogenesis of severe periodontitis includes herpesvirus‐bacteria coinfection. This
article evaluates the pathogenicity of herpesviruses (cytomegalovirus and Epstein‐Barr …

[HTML][HTML] The plasma level of soluble urokinase receptor is elevated in patients with Streptococcus pneumoniae bacteraemia and predicts mortality

P Wittenhagen, G Kronborg, N Weis, H Nielsen… - Clinical Microbiology …, 2004 - Elsevier
This multicentre prospective study was conducted to investigate whether the level of the
soluble form of urokinase-type plasminogen activator receptor (suPAR) is elevated during …

Pediatric respiratory infections by Mycoplasma pneumoniae

KY Lee - Expert review of anti-infective therapy, 2008 - Taylor & Francis
Mycoplasma pneumoniae is one of the most common agents of community-acquired
pneumonia in children and young adults. Although M. pneumoniae is a small bacterium that …

Animal Models of Streptococcus pneumoniae Disease

D Chiavolini, G Pozzi, S Ricci - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Streptococcus pneumoniae is a colonizer of human nasopharynx, but it is also an important
pathogen responsible for high morbidity, high mortality, numerous disabilities, and high …