DEAD-and DExH-box ATPases (DDX/DHXs) are abundant and highly conserved cellular
enzymes ubiquitously involved in RNA processing. By remodeling RNA–RNA and RNA …

C-terminal domain nuclear envelope phosphatase 1 (CTDNEP1, formerly Dullard) is a
member of the newly emerging protein phosphatases and has been recognized in neuronal …

Post-transcriptional mechanisms are fundamental safeguards of progenitor cell identity and
are often dysregulated in cancer. Here, we identified regulators of P-bodies as crucial …

Transposable elements are important sources of miRNA, long non-coding RNAs genes, and
their targets in the composition of protein-coding genes in plants and animals. Therefore, the …

Nonoptimal synonymous codons repress gene expression, but the underlying mechanisms
are poorly understood. We and others have previously shown that nonoptimal codons slow …

The DEAD-box proteins, one family of RNA-binding proteins (RBPs), participate in post-
transcriptional regulation of gene expression with multiple aspects. Among them, DDX6 is …

Neurodevelopmental disorders (NDDs) represent a large group of disorders with an onset in
the neonatal or early childhood period; NDDs include intellectual disability (ID), autism …

Colorectal cancer (CRC) is the third most commonly diagnosed and the second cancer-
related death worldwide, leading to more than 0.9 million deaths every year. Unfortunately …

Dilated cardiomyopathy (DCM) encompasses various acquired or genetic diseases sharing
a common phenotype. The understanding of pathogenetic mechanisms and the …

Purpose Infertility remains a human health burden globally. Only a fraction of embryos
produced via assisted reproductive technologies (ARTs) develop to the blastocyst stage in …