Transcriptome studies reveal pervasive transcription of complex genomes, such as those of
mammals. Despite popular arguments for functionality of most, if not all, of these transcripts …

Do long noncoding RNAs (lncRNAs) contribute little or substantively to human biology? To
address how lncRNA loci and their transcripts, structures, interactions, and functions …

The genomes of large multicellular eukaryotes are mostly comprised of non-protein coding
DNA. Although there has been much agreement that a small fraction of these genomes has …

Prior to the sequencing of the human genome, it was presumed that most of the DNA coded
for proteins. However, with the advent of next-generation sequencing, it has now been …

Thousands of genes encoding long noncoding RNAs (lncRNAs) have been identified in all
vertebrate genomes thus far examined. The list of lncRNAs partaking in arguably important …

Reference-quality genomes are expected to provide a resource for studying gene structure,
function, and evolution. However, often genes of interest are not completely or accurately …

Our recent ability to sequence entire genomes, along with all of their transcribed RNAs, has
led to the surprising finding that only∼ 1% of the human genome is used to encode proteins …

Rhododendron delavayi Franch. is globally famous as an ornamental plant. Its distribution in
southwest China covers several different habitats and environments. However, not much …

Genomes encode for genes and non-coding DNA, both capable of transcriptional activity.
However, unlike canonical genes, many transcripts from non-coding DNA have limited …

It is known that more than 70% of mammalian genomes are transcribed, yet the vast majority
of transcripts do not code for proteins. Are these noncoding transcripts merely transcriptional …