Toxoplasmosis: a pathway to neuropsychiatric disorders
Toxoplasma gondii is an obligate intracellular parasite that resides, in a latent form, in the
human central nervous system. Infection with Toxoplasma drastically alters the behaviour of …
human central nervous system. Infection with Toxoplasma drastically alters the behaviour of …
Dense granule biogenesis, secretion, and function in Toxoplasma gondii
MB Griffith, CS Pearce… - Journal of Eukaryotic …, 2022 - Wiley Online Library
Toxoplasma gondii is an obligate intracellular parasite and the causative agent of
Toxoplasmosis. A key to understanding and treating the disease lies with determining how …
Toxoplasmosis. A key to understanding and treating the disease lies with determining how …
[HTML][HTML] Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13
The emergence of artemisinin (ART) resistance in Plasmodium falciparum intra-erythrocytic
parasites has led to increasing treatment failure rates with first-line ART-based combination …
parasites has led to increasing treatment failure rates with first-line ART-based combination …
[HTML][HTML] Characterization of a Toxoplasma effector uncovers an alternative GSK3/β-catenin-regulatory pathway of inflammation
H He, MP Brenier-Pinchart, L Braun, A Kraut… - Elife, 2018 - elifesciences.org
The intracellular parasite Toxoplasma gondii, hijacks evolutionarily conserved host
processes by delivering effector proteins into the host cell that shift gene expression in a …
processes by delivering effector proteins into the host cell that shift gene expression in a …
Reassessing the mechanics of parasite motility and host-cell invasion
I Tardieux, J Baum - Journal of Cell Biology, 2016 - rupress.org
The capacity to migrate is fundamental to multicellular and single-celled life. Apicomplexan
parasites, an ancient protozoan clade that includes malaria parasites (Plasmodium) and …
parasites, an ancient protozoan clade that includes malaria parasites (Plasmodium) and …
[HTML][HTML] Transcriptional modification of host cells harboring Toxoplasma gondii bradyzoites prevents IFN gamma-mediated cell death
Toxoplasma gondii develops a latent infection in the muscle and central nervous system that
acts as a reservoir for acute-stage reactivation in vulnerable patients. Little is understood …
acts as a reservoir for acute-stage reactivation in vulnerable patients. Little is understood …
The broad host range pathogen Sclerotinia sclerotiorum produces multiple effector proteins that induce host cell death intracellularly
Sclerotinia sclerotiorum is a broad host range necrotrophic fungal pathogen, which causes
disease on many economically important crop species. S. sclerotiorum has been shown to …
disease on many economically important crop species. S. sclerotiorum has been shown to …
Aspartyl protease 5 matures dense granule proteins that reside at the host-parasite interface in Toxoplasma gondii
Toxoplasma gondii infects approximately 30% of the world's population, causing disease
primarily during pregnancy and in individuals with weakened immune systems. Toxoplasma …
primarily during pregnancy and in individuals with weakened immune systems. Toxoplasma …
Translocation of effector proteins into host cells by Toxoplasma gondii
S Rastogi, AM Cygan, JC Boothroyd - Current opinion in microbiology, 2019 - Elsevier
Highlights•Toxoplasma introduces ROP and GRA effectors into host cells to coopt host
functions.•ROP effector secretion occurs during invasion via an unknown mechanism.•MYR1 …
functions.•ROP effector secretion occurs during invasion via an unknown mechanism.•MYR1 …
Phosphorylation in the Plasmodium falciparum Proteome: A Meta-Analysis of Publicly Available Data Sets
OJM Camacho, KA Ramsbottom… - Journal of Proteome …, 2023 - ACS Publications
Malaria is a deadly disease caused by Apicomplexan parasites of the Plasmodium genus.
Several species of the Plasmodium genus are known to be infectious to humans, of which P …
Several species of the Plasmodium genus are known to be infectious to humans, of which P …