Breast Cancer in Men Breast cancer in men accounts for about 1% of all breast cancers and
is mainly estrogen-receptor–positive. Few prospective studies of treatment in men have …

Breast cancer is the most common malignancy among females. 5%–10% of breast cancer
cases are hereditary and are caused by pathogenic mutations in the considered reference …

Germline mutations in BRCA1 and BRCA2 confer high risks of breast and ovarian cancer,
but the average magnitude of these risks is uncertain and may depend on the context …

Risks of breast and ovarian cancer were determined for Ashkenazi Jewish women with
inherited mutations in the tumor suppressor genes BRCA1 and BRCA2. We selected 1008 …

Breast cancer is the commonest cause of cancer death in women worldwide. Rates vary
about five-fold around the world, but they are increasing in regions that until recently had low …

Background Many cases of hereditary breast cancer are due to mutations in either the
BRCA1 or the BRCA2 gene. The histopathological changes in these cancers are often …

Background: BRCA1 and BRCA2 mutations in general populations and in various types of
cancers have not been well characterized. We investigated the presence of these mutations …

BACKGROUND & AIMS:: Germline mutations in CDH1 are known to cause hereditary
diffuse gastric cancer (HDGC). Breast and colorectal cancer have also been reported in …

Biomarkers are assayed to assess biological and pathological status. Recent advances in
high-throughput proteomic technology provide opportunities for developing next generation …

Hereditary breast and ovarian cancer due to mutations in the BRCA1 and BRCA2 genes is
the most common cause of hereditary forms of both breast and ovarian cancer. The overall …