The majority of the human genome is not translated into proteins but can be transcribed into
RNA. Even though the resulting non-coding RNAs (ncRNAs) do not encode for proteins …

The tripartite motif (TRIM) protein family is a highly conserved group of E3 ligases with 77
members known in the human, most of which consist of a RING-finger domain, one or two B …

Long noncoding RNAs (lncRNAs) have been associated with hepatocellular carcinoma
(HCC), but the underlying molecular mechanisms of their specific association with …

The Adenosine diphosphate-Ribosylation Factor (ARF) family belongs to the RAS
superfamily of small GTPases and is involved in a wide variety of physiological processes …

Tripartite motif (TRIM) family is assigned to RING-finger-containing ligases harboring the
largest number of proteins in E3 ubiquitin ligating enzymes. E3 ubiquitin ligases target the …

Protein inhibitor of activated STAT (PIAS) proteins are activation-suppressing proteins for
signal transducer and activator of transcription (STAT), which involves gene transcriptional …

Background Tripartite motif (TRIM) family proteins have more than 80 members and are
widely found in various eukaryotic cells. Most TRIM family proteins participate in the …

Background Our previous study has demonstrated that hepatocyte nuclear factor 1α
(HNF1α) exerts potent therapeutic effects on hepatocellular carcinoma (HCC). However, the …

Hepatocellular carcinoma (HCC) is a tumor with poor prognosis and frequently aggressive.
The development of HCC is associated with fibrosis and cirrhosis, which mainly results from …

Polypyrimidine tract‐binding protein 1 (PTBP1) is one of the most investigated
multifunctional RNA‐binding proteins (RBP), controlling almost all steps of mRNA …