This review provides a comprehensive landscape of HGF/c-MET (hepatocyte growth factor
(HGF)/mesenchymal–epithelial transition factor (c-MET)) signaling pathway in cancers. First …

Signaling pathways that mediate the normal functions of growth factors are commonly
subverted in cancer. Oncogenes identified by a variety of approaches have been shown to …

Hepatocyte growth factor (HGF) is a plasminogen-like protein thought to be a humoral
mediator of liver regeneration. A 145-kilodalton tyrosyl phosphoprotein observed in rapid …

Hepatocyte Growth Factor (HGF, also known as Scatter Factor) is a powerful mitogen or
motility factor in different cells, acting through the tyrosine kinase receptor encoded by the …

Human embryonic stem (ES) cells are pluripotent cells derived from the inner cell mass of in
vitro fertilized human blastocysts. We examined the potential of eight growth factors [basic …

HEPATOCYTE growth factor/scatter factor (HGF/SF) functions as a mitogen, motogen and
morphogen for a variety of cultured cells1–7. The genes for HGF/SF and its receptor (the c …

A set of growth arrest-specific genes (gas) whose expression is negatively regulated after
serum induction has previously been described (C. Schneider, RM King, and L. Philipson …

We have previously shown that Madin-Darby canine kidney (MDCK) epithelial cells grown in
collagen gels in the presence of fibroblasts orfibroblast-conditioned medium (CM) form …

Activating mutations in receptor tyrosine kinases play a critical role in oncogenesis. Despite
evidence that Met kinase is deregulated in human cancer, the role of activating mutations in …

Scatter Factor (SF) is a fibroblast‐secreted protein which promotes motility and matrix
invasion of epithelial cells. Hepatocyte Growth Factor (HGF) is a powerful mitogen for …