Investigating the molecular mechanisms of learning and memory using Caenorhabditis elegans

A Rahmani, YL Chew - Journal of Neurochemistry, 2021 - Wiley Online Library
Learning is an essential biological process for survival since it facilitates behavioural
plasticity in response to environmental changes. This process is mediated by a wide variety …

Zika virus neuropathogenesis: The different brain cells, host factors and mechanisms involved

TV Komarasamy, NAA Adnan, W James… - Frontiers in …, 2022 - frontiersin.org
Zika virus (ZIKV), despite being discovered six decades earlier, became a major health
concern only after an epidemic in French Polynesia and an increase in the number of …

Sensing the world and its dangers: an evolutionary perspective in neuroimmunology

A Kraus, KM Buckley, I Salinas - Elife, 2021 - elifesciences.org
Detecting danger is key to the survival and success of all species. Animal nervous and
immune systems cooperate to optimize danger detection. Preceding studies have …

Whole‐transcriptome sequencing identifies neuroinflammation, metabolism and blood–brain barrier related processes in the hippocampus of aged mice during …

Z Suo, J Yang, B Zhou, Y Qu, W Xu, M Li… - CNS Neuroscience …, 2022 - Wiley Online Library
Aim Perioperative neurocognitive disorders (PND) occur frequently after surgery and
anesthesia, especially in aged patients. Previous studies have shown multiple PND related …

Epigenetics of traumatic stress: The association of NR3C1 methylation and posttraumatic stress disorder symptom changes in response to narrative exposure therapy

S Wilker, V Vukojevic, A Schneider, A Pfeiffer… - Translational …, 2023 - nature.com
Epigenetic processes allow plasticity in gene regulation in response to significant
environmental events. Accumulating evidence suggests that effective psychotherapy is …

Differential effects of APOE genotype on MicroRNA cargo of cerebrospinal fluid extracellular vesicles in females with Alzheimer's disease compared to males

US Sandau, TJ McFarland, SJ Smith… - Frontiers in Cell and …, 2022 - frontiersin.org
Multiple biological factors, including age, sex, and genetics, influence Alzheimer's disease
(AD) risk. Of the 6.2 million Americans living with Alzheimer's dementia in 2021, 3.8 million …

Functional diversity of neuronal cell adhesion and recognition molecule L1CAM through proteolytic cleavage

II Stoyanova, D Lutz - Cells, 2022 - mdpi.com
The neuronal cell adhesion and recognition molecule L1 does not only 'keep cells
together'by way of homophilic and heterophilic interactions, but can also promote cell …

Analyses of GWAS signal using GRIN identify additional genes contributing to suicidal behavior

KA Sullivan, M Lane, M Cashman, JI Miller… - Communications …, 2024 - nature.com
Genome-wide association studies (GWAS) identify genetic variants underlying complex
traits but are limited by stringent genome-wide significance thresholds. We present GRIN …

DNA methylation changes following narrative exposure therapy in a randomized controlled trial with female former child soldiers

S Carleial, D Nätt, E Unternährer, T Elbert, K Robjant… - Scientific reports, 2021 - nature.com
The aftermath of traumatization lives on in the neural and epigenetic traces creating a
momentum of affliction in the psychological and social realm. Can psychotherapy reorganise …

Neuromechanobiology: an expanding field driven by the force of greater focus

CT Motz, V Kabat, T Saxena… - Advanced …, 2021 - Wiley Online Library
The brain processes information by transmitting signals through highly connected and
dynamic networks of neurons. Neurons use specific cellular structures, including axons …