Phoenix dactylifera L.: An Overview of Phytochemical Constituents and Impact on Women's Health

EM AbouZeid, AH Afifi, RA Hussei… - Chemistry & …, 2024 - Wiley Online Library
Phoenix dactylifera L.(date palm) is the most significant member of the palm family
(Arecaceae), particularly in the Middle East and Arab World. It is a valuable source of both …

Novel quercetin encapsulated chitosan functionalized copper oxide nanoparticles as anti-breast cancer agent via regulating p53 in rat model

AM Elsayed, NM Sherif, NS Hassan, F Althobaiti… - International Journal of …, 2021 - Elsevier
This study was designed to present a new quercetin encapsulated chitosan functionalized
copper oxide nanoparticle (CuO-ChNPs-Q) and assessed its anti-breast cancer activity both …

Immune checkpoint inhibitor-associated cardiovascular toxicities: A review

G Liu, T Chen, X Zhang, B Hu, H Shi - Heliyon, 2024 - cell.com
Immune checkpoint inhibitors (ICIs) have revolutionary effects on therapeutic strategies for
multiple malignancies. Their efficacy depends on their ability to reactivate the host immune …

The effect of encapsulated apigenin nanoparticles on HePG-2 cells through regulation of P53

MM Mabrouk Zayed, HA Sahyon, NAN Hanafy… - Pharmaceutics, 2022 - mdpi.com
Apigenin (Ap) is one of the most important natural flavonoids that has potent anticancer
activity. This study was designed, for the first time, to load Ap into chitosan to improve its …

[HTML][HTML] The potential antioxidant bioactivity of date palm fruit against gentamicin-mediated hepato-renal injury in male albino rats

A Abdeen, A Samir, A Elkomy, M Aboubaker… - Biomedicine & …, 2021 - Elsevier
Gentamicin (GM) is a commonly prescribed antimicrobial drug used for treatment of
infections but associated hepatic and renal complications restrict its efficacy. Overproduction …

The anti-toxic effect of the date palm fruit extract loaded on chitosan nanoparticles against CCl4-induced liver fibrosis in a mouse model

HA Sahyon, NM El-Shafai, I El-Mehasseb… - International Journal of …, 2023 - Elsevier
The liver is the most important organ in the body. Hepatocyte oxidative damage occurs to
excess ROS. Liver fibrosis is a mechanism that the immune system uses to treat extreme …

Investigation of the anti-hyperglycemic and antioxidant effects of wheat bread supplemented with onion peel extract and onion powder in diabetic rats

S Masood, A Rehman, S Bashir, M El Shazly… - Journal of Diabetes & …, 2021 - Springer
Aim Onion is one of the commonly cultivated and consumed vegetables rich in nutrients and
phytochemicals. Various nutraceuticals are found in the outer fleshy layers and dry peel of …

Phytochemical analysis and nephroprotective potential of Ajwa date in doxorubicin‐induced nephrotoxicity rats: Biochemical and molecular docking approaches

OAS Baothman, HN Altayb, MA Zeyadi… - Food Science & …, 2023 - Wiley Online Library
The purpose of this study is to evaluate the likely defensive impact of Ajwa date aqueous
extract (AJDAE) in alleviating the nephrotoxicity generated by doxorubicin (DOX) injection in …

Antimicrobial, anticancer and antioxidant activities of nano-heart of Phoenix dactylifera tree extract loaded chitosan nanoparticles: In vitro and in vivo study

HA Sahyon, SA Al-Harbi - International journal of biological …, 2020 - Elsevier
This study aimed to present a new heart of P. dactylifera (HP) extract loaded chitosan
nanoparticles and estimate its anticancer, antimicrobial, antioxidant activity and free radical …

Pirfenidone and vitamin D ameliorate cardiac fibrosis induced by doxorubicin in Ehrlich ascites carcinoma bearing mice: Modulation of monocyte chemoattractant …

MA Saleh, SA Antar, RM Hazem, MF El-Azab - Pharmaceuticals, 2020 - mdpi.com
Treatment of breast cancer with doxorubicin causes numerous side effects, of which cardiac
fibrosis is considered the main one. This study was designed to investigate the underlying …