Extracellular vesicles (EVs) are heterogeneous membranous particles released from the
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …

Protein–RNA interactions have crucial roles in various cellular activities, which, when
dysregulated, can lead to a range of human diseases. The identification of small molecules …

The RNA-binding proteins (RBPs) are critical trans factors that associate with specific cis
elements present in mRNAs whose stability and translation are subject to regulation. The …

Traditionally majority of eukaryotic gene expression is influenced by transcriptional and post-
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …

The control of eukaryotic gene expression occurs at multiple levels, from transcription to
messenger RNA processing, transport, localization, turnover, and translation. RNA-binding …

Patients diagnosed with metastatic breast cancer have a dismal 5-year survival rate of only
24%. The RNA-binding protein Hu antigen R (HuR) is upregulated in breast cancer, and …

Highlights•RNA-binding proteins (RBPs) are essential for tumorigenesis, immune evasion,
invasion, migration and metastasis, hence promising drug targets in cancer therapy.•Small …

Glutaminase (GLS) is directly related to cell growth and tumor progression, making it a target
for cancer treatment. The RNA-binding protein HuR (encoded by the ELAVL1 gene) …

Abstract Salvia miltiorrhiza Bunge (Danshen), a famous traditional Chinese herb, has been
used clinically for the treatment of various diseases for centuries. Document data showed …

Cancer cells can develop a strong addiction to discrete molecular regulators, which control
the aberrant gene expression programs that drive and maintain the cancer phenotype. Here …