Innate immunity at the crossroads of healthy brain maturation and neurodevelopmental disorders

KE Zengeler, JR Lukens - Nature Reviews Immunology, 2021 - nature.com
The immune and nervous systems have unique developmental trajectories that individually
build intricate networks of cells with highly specialized functions. These two systems have …

Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery

J Deprez, G Lajoinie, Y Engelen, SC De Smedt… - Advanced drug delivery …, 2021 - Elsevier
Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …

Disrupting the blood–brain barrier by focused ultrasound induces sterile inflammation

ZI Kovacs, S Kim, N Jikaria, F Qureshi… - Proceedings of the …, 2017 - National Acad Sciences
MRI-guided pulsed focused ultrasound (pFUS) combined with systemic infusion of
ultrasound contrast agent microbubbles (MB) causes localized blood–brain barrier (BBB) …

Proinflammatory cytokines, aging, and age-related diseases

M Michaud, L Balardy, G Moulis, C Gaudin… - Journal of the American …, 2013 - Elsevier
Inflammation is a physiological process that repairs tissues in response to endogenous or
exogenous aggressions. Nevertheless, a chronic state of inflammation may have detrimental …

[HTML][HTML] Inflammation after ischemic stroke: the role of leukocytes and glial cells

JY Kim, J Park, JY Chang, SH Kim… - Experimental …, 2016 - ncbi.nlm.nih.gov
The immune response after stroke is known to play a major role in ischemic brain
pathobiology. The inflammatory signals released by immune mediators activated by brain …

Ischemic cell death in brain neurons

P Lipton - Physiological reviews, 1999 - journals.physiology.org
This review is directed at understanding how neuronal death occurs in two distinct insults,
global ischemia and focal ischemia. These are the two principal rodent models for human …

Molecular inflammation: underpinnings of aging and age-related diseases

HY Chung, M Cesari, S Anton, E Marzetti… - Ageing research …, 2009 - Elsevier
Recent scientific studies have advanced the notion of chronic inflammation as a major risk
factor underlying aging and age-related diseases. In this review, low-grade, unresolved …

The induction of pain: an integrative review

MJ Millan - Progress in neurobiology, 1999 - Elsevier
The highly disagreeable sensation of pain results from an extraordinarily complex and
interactive series of mechanisms integrated at all levels of the neuroaxis, from the periphery …

Recent advances in iron oxide nanocrystal technology for medical imaging

C Corot, P Robert, JM Idée, M Port - Advanced drug delivery reviews, 2006 - Elsevier
Superparamagnetic iron oxide particles (SPIO and USPIO) have a variety of applications in
molecular and cellular imaging. Most of the recent research has concerned cellular imaging …

Molecular and cellular mechanisms of pulmonary fibrosis

NW Todd, IG Luzina, SP Atamas - Fibrogenesis & tissue repair, 2012 - Springer
Pulmonary fibrosis is a chronic lung disease characterized by excessive accumulation of
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …