The crystalline lens is a transparent and refractive biconvex structure formed by lens
epithelial cells (LECs) and lens fibers. Lens opacity, also known as cataracts, is the leading …

Congenital cataracts, the most common cause of visual impairment and blindness in
children worldwide, have diverse etiologies. According to statistics analysis, about one …

Congenital cataract is a rare eye disease, one of the leading treatable causes of low vision
in children worldwide. Hereditary cataracts can be divided in syndromic and non-syndromic …

Congenital cataract is a challenging ophthalmological disorder which can cause severe
visual loss. It can be diagnosed at birth or during the first year of life. Early diagnosis and …

Infantile and childhood-onset cataracts form a heterogeneous group of disorders; among the
many genetic causes, numerous pathogenic variants in additional genes associated with …

Congenital cataract (CC) is a significant cause of childhood blindness worldwide. CC is a
genetically heterogeneous disease because mutations in over 40 genes have been …

Autosomal dominant congenital cataract (ADCC), the most common hereditary disease, is a
major cause of eye disease in children. Due to its high genetic and clinical heterogeneity …

Congenital cataract, which refers to lenticular opacity diagnosed at birth or more commonly
during the first year of life, is one of the leading causes of childhood blindness. Molecular …

Introdução: A leucocoria se define pelo reflexo pupilar branco, róseo ou amarelo
esbranquiçado evidenciado no teste de Bruckner, que deve ser realizado ao nascimento e …

Introduction Variants in the two lens-expressed gap junction genes GJA3 and GJA8 are
among the most common causes of inherited pediatric cataract. These two genes alone …