Arachidonic acid metabolism and kidney inflammation

T Wang, X Fu, Q Chen, JK Patra, D Wang… - International journal of …, 2019 - mdpi.com
As a major component of cell membrane lipids, Arachidonic acid (AA), being a major
component of the cell membrane lipid content, is mainly metabolized by three kinds of …

Cancer-related inflammation and treatment effectiveness

CI Diakos, KA Charles, DC McMillan… - The Lancet …, 2014 - thelancet.com
Inflammation is a recognised hallmark of cancer that substantially contributes to the
development and progression of malignancies. In established cancers, there is increasing …

The role of the systemic inflammatory response in predicting outcomes in patients with operable cancer: systematic review and meta-analysis

RD Dolan, J Lim, ST McSorley, PG Horgan… - Scientific reports, 2017 - nature.com
Cancer remains a leading causes of death worldwide and an elevated systemic
inflammatory response (SIR) is associated with reduced survival in patients with operable …

Exploiting the critical perioperative period to improve long-term cancer outcomes

M Horowitz, E Neeman, E Sharon… - Nature reviews Clinical …, 2015 - nature.com
Evidence suggests that the perioperative period and the excision of the primary tumour can
promote the development of metastases—the main cause of cancer-related mortality. This …

Prognostic significance of neutrophil-to-lymphocyte ratio in non-small cell lung cancer: a meta-analysis

XB Gu, T Tian, XJ Tian, XJ Zhang - Scientific reports, 2015 - nature.com
Published data on the prognostic significance of neutrophil-to-lymphocyte ratio (NLR) in non-
small cell lung cancer (NSCLC) are controversial. We performed a meta-analysis to more …

Neutrophil-to-lymphocyte ratio as an early marker of outcomes in patients with advanced non-small-cell lung cancer treated with nivolumab

A Nakaya, T Kurata, H Yoshioka, Y Takeyasu… - International journal of …, 2018 - Springer
Background There is an unmet need to identify markers that predict the response to
nivolumab in patients with non-small-cell lung cancer (NSCLC). The neutrophil-to …

Prognostic role of the neutrophil–lymphocyte ratio in renal cell carcinoma: a meta-analysis

K Hu, L Lou, J Ye, S Zhang - BMJ open, 2015 - bmjopen.bmj.com
Objective Increasing evidence suggests that cancer-associated inflammation is associated
with poor prognosis in patients with cancer. The role of the neutrophil–lymphocyte ratio …

[HTML][HTML] Prognostic value of neutrophil-to-lymphocyte ratio in breast cancer

J Chen, Q Deng, Y Pan, B He, H Ying, H Sun, X Liu… - FEBS open bio, 2015 - Elsevier
Inflammation is an essential component of pathogenesis and progression of cancer. A high
neutrophil-to-lymphocyte ratio (NLR) is considered as a prognostic indicator for breast …

Harnessing cancer immunotherapy during the unexploited immediate perioperative period

P Matzner, E Sandbank, E Neeman, O Zmora… - Nature reviews Clinical …, 2020 - nature.com
The immediate perioperative period (days before and after surgery) is hypothesized to be
crucial in determining long-term cancer outcomes: during this short period, numerous …

[HTML][HTML] Preoperative systemic inflammation and perioperative myocardial injury: prospective observational multicentre cohort study of patients undergoing non …

GL Ackland, TEF Abbott, D Cain, MR Edwards… - British journal of …, 2019 - Elsevier
Background Systemic inflammation is pivotal in the pathogenesis of cardiovascular disease.
As inflammation can directly cause cardiomyocyte injury, we hypothesised that established …