Hierarchically oriented organization in supramolecular peptide crystals

C Yuan, W Ji, R Xing, J Li, E Gazit, X Yan - Nature Reviews Chemistry, 2019 - nature.com
Hierarchical self-assembly and crystallization with long-range ordered spatial arrangement
is ubiquitous in nature and plays an essential role in the regulation of structures and …

Nucleation and growth of amino acid and peptide supramolecular polymers through liquid–liquid phase separation

C Yuan, A Levin, W Chen, R Xing, Q Zou… - Angewandte Chemie …, 2019 - Wiley Online Library
The transition of peptides and proteins from the solution phase into fibrillar structures is a
general phenomenon encountered in functional and aberrant biology and is increasingly …

Peptide self-assembly through liquid-liquid phase separation

C Yuan, Q Li, R Xing, J Li, X Yan - Chem, 2023 - cell.com
Peptide self-assembly provides an innovative strategy for not only establishing an ideal
research model to understand life phenomena but also for constructing sophisticated …

Enzymatic noncovalent synthesis

H He, W Tan, J Guo, M Yi, AN Shy, B Xu - Chemical reviews, 2020 - ACS Publications
Enzymatic reactions and noncovalent (ie, supramolecular) interactions are two fundamental
nongenetic attributes of life. Enzymatic noncovalent synthesis (ENS) refers to a process …

Supramolecular biomaterials

MJ Webber, EA Appel, EW Meijer, R Langer - Nature materials, 2016 - nature.com
Polymers, ceramics and metals have historically dominated the application of materials in
medicine. Yet rationally designed materials that exploit specific, directional, tunable and …

Small angle X-ray scattering for nanoparticle research

T Li, AJ Senesi, B Lee - Chemical reviews, 2016 - ACS Publications
X-ray scattering is a structural characterization tool that has impacted diverse fields of study.
It is unique in its ability to examine materials in real time and under realistic sample …

Thermoresponsive actuation enabled by permittivity switching in an electrostatically anisotropic hydrogel

YS Kim, M Liu, Y Ishida, Y Ebina, M Osada, T Sasaki… - Nature materials, 2015 - nature.com
Electrostatic repulsion, long used for attenuating surface friction,, is not typically employed
for the design of bulk structural materials. We recently developed a hydrogel with a layered …

Self-assembling prodrugs

AG Cheetham, RW Chakroun, W Ma… - Chemical Society Reviews, 2017 - pubs.rsc.org
Covalent modification of therapeutic compounds is a clinically proven strategy to devise
prodrugs with enhanced treatment efficacies. This prodrug strategy relies on the modified …

Functional supramolecular polymers

T Aida, EW Meijer, SI Stupp - Science, 2012 - science.org
Supramolecular polymers can be random and entangled coils with the mechanical
properties of plastics and elastomers, but with great capacity for processability, recycling …

Energy landscapes and functions of supramolecular systems

F Tantakitti, J Boekhoven, X Wang, RV Kazantsev… - Nature materials, 2016 - nature.com
By means of two supramolecular systems—peptide amphiphiles engaged in hydrogen-
bonded β-sheets, and chromophore amphiphiles driven to assemble by π-orbital overlaps …