[HTML][HTML] Nanovaccines: a game changing approach in the fight against infectious diseases

MAH Abusalah, H Chopra, A Sharma… - Biomedicine & …, 2023 - Elsevier
The field of nanotechnology has revolutionised global attempts to prevent, treat, and
eradicate infectious diseases in the foreseen future. Nanovaccines have proven to be a …

Host–Pathogen interactions influencing zoonotic spillover potential and transmission in humans

B Escudero-Pérez, A Lalande, C Mathieu, P Lawrence - Viruses, 2023 - mdpi.com
Emerging infectious diseases of zoonotic origin are an ever-increasing public health risk
and economic burden. The factors that determine if and when an animal virus is able to spill …

A SARS-CoV-2 vaccine candidate would likely match all currently circulating variants

B Dearlove, E Lewitus, H Bai, Y Li… - Proceedings of the …, 2020 - National Acad Sciences
The magnitude of the COVID-19 pandemic underscores the urgency for a safe and effective
vaccine. Many vaccine candidates focus on the Spike protein, as it is targeted by …

Low genetic diversity may be an Achilles heel of SARS-CoV-2

JW Rausch, AA Capoferri… - Proceedings of the …, 2020 - National Acad Sciences
Scientists worldwide are racing to develop effective vaccines against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID-19 …

Nanovaccines against animal pathogens: The latest findings

CT Celis-Giraldo, J López-Abán, A Muro, MA Patarroyo… - Vaccines, 2021 - mdpi.com
Nowadays, safe and efficacious vaccines represent powerful and cost-effective tools for
global health and economic growth. In the veterinary field, these are undoubtedly key tools …

Pathogenicity and Virulence of Ebolaviruses with Species-and Variant-specificity

S Yamaoka, H Ebihara - Virulence, 2021 - Taylor & Francis
Ebola virus (EBOV), belonging to the species Zaire ebolavirus in the genus Ebolavirus,
causes a severe febrile illness in humans with case fatality rates (CFRs) up to 90%. While …

N123I mutation in the ALV-J receptor-binding domain region enhances viral replication ability by increasing the binding affinity with chNHE1

M Yu, Y Zhang, L Zhang, S Wang, Y Liu, Z Xu… - PloS …, 2024 - journals.plos.org
The subgroup J avian leukosis virus (ALV-J), a retrovirus, uses its gp85 protein to bind to the
receptor, the chicken sodium hydrogen exchanger isoform 1 (chNHE1), facilitating viral …

[HTML][HTML] Comparison of epidemiological and clinical characteristics of COVID-19 patients with and without Wuhan exposure history in Zhejiang Province, China

J Lian, H Cai, S Hao, X Jin, X Zhang… - Journal of Zhejiang …, 2020 - ncbi.nlm.nih.gov
Background: A novel coronavirus called severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), first identified in Wuhan, China, has been rapidly spreading around the …

[HTML][HTML] Natural history of Ebola virus disease in rhesus monkeys shows viral variant emergence dynamics and tissue-specific host responses

E Normandin, S Triana, SS Raju, TCT Lan… - Cell Genomics, 2023 - cell.com
Ebola virus (EBOV) causes Ebola virus disease (EVD), marked by severe hemorrhagic
fever; however, the mechanisms underlying the disease remain unclear. To assess the …

Molecular characterization of the 2022 Sudan virus disease outbreak in Uganda

S Balinandi, S Whitmer, S Mulei, C Nassuna… - Journal of …, 2023 - Am Soc Microbiol
Uganda experienced five Ebola disease outbreaks caused by Bundibugyo virus (n= 1) and
Sudan virus (SUDV)(n= 4) from 2000 to 2021. On 20 September 2022, Uganda declared a …