Extracellular matrix (ECM) derived components are emerging sources for the engineering of
biomaterials that are capable of inducing desirable cell-specific responses. This review …

An excessive foreign body response (FBR) has contributed to the adverse events associated
with polypropylene mesh usage for augmenting pelvic organ prolapse surgery …

Vaginal meshes used in the treatment of stress urinary incontinence (SUI) and pelvic organ
prolapse (POP) have produced highly variable outcomes, causing life-changing …

Polypropylene meshes used in pelvic organ prolapse (POP) repair are hampered by
complications. Most POP meshes are highly unstable after tensioning ex vivo, as evidenced …

The entry of subcutaneous extracellular matrix proteins into the circulation is a key step in
hemostasis initiation after vascular injury. However, in cases of severe trauma, extracellular …

Congenital vaginal anomalies and pelvic organ prolapse affect different age groups of
women and both have significant negative impacts on patients' psychological well-being …

Transvaginal meshes repair for treating pelvic organ prolapse (POP) was halted by the US
Food and Drug Administration (FDA) because they can lead to severe complications …

Stress urinary incontinence (SUI) and pelvic organ prolapse (POP) are conditions which
result in significant physical, mental and social consequences for women worldwide. The …

Pelvic organ prolapse (POP) is a hidden women's health disorder that impacts 1 in 4 women
across all age groups. Surgical intervention has been the only treatment option, often …

Uterosacral ligament suspension (USLS) is a common surgical treatment for pelvic organ
prolapse (POP). However, the relatively high failure rate of up to 40% underscores a strong …