Innovative treatment strategies to accelerate wound healing: trajectory and recent advancements
P Kolimi, S Narala, D Nyavanandi, AAA Youssef… - Cells, 2022 - mdpi.com
Wound healing is highly specialized dynamic multiple phase process for the repair of
damaged/injured tissues through an intricate mechanism. Any failure in the normal wound …
damaged/injured tissues through an intricate mechanism. Any failure in the normal wound …
[HTML][HTML] TGF-β in developmental and fibrogenic EMTs
JH Lee, J Massagué - Seminars in cancer biology, 2022 - Elsevier
TGF-β plays a prominent role as an inducer of epithelial-mesenchymal transitions (EMTs)
during development and wound healing and in disease conditions such as fibrosis and …
during development and wound healing and in disease conditions such as fibrosis and …
Linking EMT programmes to normal and neoplastic epithelial stem cells
AW Lambert, RA Weinberg - Nature Reviews Cancer, 2021 - nature.com
Epithelial stem cells serve critical physiological functions in the generation, maintenance
and repair of diverse tissues through their ability to self-renew and spawn more specialized …
and repair of diverse tissues through their ability to self-renew and spawn more specialized …
Interleukin-17 governs hypoxic adaptation of injured epithelium
Mammalian cells autonomously activate hypoxia-inducible transcription factors (HIFs) to
ensure survival in low-oxygen environments. We report here that injury-induced hypoxia is …
ensure survival in low-oxygen environments. We report here that injury-induced hypoxia is …
Cellular and molecular mechanisms of skin wound healing
Wound healing is a complex process that involves the coordinated actions of many different
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …
[HTML][HTML] Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis
Y Feng, M Spezia, S Huang, C Yuan, Z Zeng, L Zhang… - Genes & diseases, 2018 - Elsevier
As the most commonly occurring cancer in women worldwide, breast cancer poses a
formidable public health challenge on a global scale. Breast cancer consists of a group of …
formidable public health challenge on a global scale. Breast cancer consists of a group of …
Chitosan-based self-healing hydrogel dressing for wound healing
Skin has strong self-regenerative capacity, while severe skin defects do not heal without
appropriate treatment. Therefore, in order to cover the wound sites and hasten the healing …
appropriate treatment. Therefore, in order to cover the wound sites and hasten the healing …
The extracellular matrix dictates regional competence for tumour initiation
N Bansaccal, P Vieugue, R Sarate, Y Song… - Nature, 2023 - nature.com
The skin epidermis is constantly renewed throughout life,. Disruption of the balance between
renewal and differentiation can lead to uncontrolled growth and tumour initiation. However …
renewal and differentiation can lead to uncontrolled growth and tumour initiation. However …
Re-epithelialization of adult skin wounds: Cellular mechanisms and therapeutic strategies
P Rousselle, F Braye, G Dayan - Advanced Drug Delivery Reviews, 2019 - Elsevier
Cutaneous wound healing in adult mammals is a complex multi-step process involving
overlapping stages of blood clot formation, inflammation, re-epithelialization, granulation …
overlapping stages of blood clot formation, inflammation, re-epithelialization, granulation …
Emerging treatment strategies in wound care
M Mirhaj, S Labbaf, M Tavakoli… - International Wound …, 2022 - Wiley Online Library
Wound healing is a complex process in tissue regeneration through which the body
responds to the dissipated cells as a result of any kind of severe injury. Diabetic and non …
responds to the dissipated cells as a result of any kind of severe injury. Diabetic and non …