Aptamers are short oligonucleotides isolated in vitro from randomized libraries that can bind
to specific molecules with high affinity, and offer a number of advantages relative to …

The rapid advancements in nucleic acid-based electrochemical sensors for implantable and
wearable applications have marked a significant leap forward in the domain of personal …

Wearable technologies for personalized monitoring require sensors that track biomarkers
often present at low levels. Cortisol—a key stress biomarker—is present in sweat at low …

Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …

Detection of analytes by means of field-effect transistors bearing ligand-specific receptors is
fundamentally limited by the shielding created by the electrical double layer (the “Debye …

Aptamers are short single-stranded DNA or RNA oligonucleotides isolated from randomized
libraries, presenting high affinity and specificity toward targets with similar to antibodies …

The continuous, real-time measurement of specific molecules in situ in the body would
greatly improve our ability to understand, diagnose, and treat disease. The vast majority of …

The classical DNA aptamer for adenosine and ATP has been the most used small molecule
binding aptamer for biosensing, imaging, and DNA nanotechnology. This sequence has …

Over the last three decades, numerous aptamer-based biosensors have been reported. The
basis of these sensors is the selective binding of target analytes by aptamers. In the last few …

L‐lactate is a key metabolite indicative of physiological states, glycolysis pathways, and
various diseases such as sepsis, heart attack, lactate acidosis, and cancer. Detection of …