Physiological and pathological roles of lipogenesis
Lipids are essential metabolites, which function as energy sources, structural components
and signalling mediators. Most cells are able to convert carbohydrates into fatty acids, which …
and signalling mediators. Most cells are able to convert carbohydrates into fatty acids, which …
Adipocyte regulation of insulin sensitivity and the risk of type 2 diabetes
A Santoro, BB Kahn - New England Journal of Medicine, 2023 - Mass Medical Soc
Adipocyte Regulation of Insulin Sensitivity and the Risk of Type 2 Diabetes | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids
Branched fatty acid (FA) esters of hydroxy FAs (HFAs; FAHFAs) are recently discovered
lipids that are conserved from yeast to mammals,. A subfamily, palmitic acid esters of …
lipids that are conserved from yeast to mammals,. A subfamily, palmitic acid esters of …
Understanding FAHFAs: From structure to metabolic regulation
K Brejchova, L Balas, V Paluchova, M Brezinova… - Progress in lipid …, 2020 - Elsevier
The discovery of branched fatty acid esters of hydroxy fatty acids (FAHFAs) in humans draw
attention of many researches to their biological effects. Although FAHFAs were originally …
attention of many researches to their biological effects. Although FAHFAs were originally …
The human islet: mini-organ with mega-impact
JT Walker, DC Saunders, M Brissova… - Endocrine …, 2021 - academic.oup.com
This review focuses on the human pancreatic islet—including its structure, cell composition,
development, function, and dysfunction. After providing a historical timeline of key …
development, function, and dysfunction. After providing a historical timeline of key …
Polyunsaturated fatty acids: conversion to lipid mediators, roles in inflammatory diseases and dietary sources
JL Harwood - International Journal of Molecular Sciences, 2023 - mdpi.com
Polyunsaturated fatty acids (PUFAs) are important components of the diet of mammals. Their
role was first established when the essential fatty acids (EFAs) linoleic acid and α-linolenic …
role was first established when the essential fatty acids (EFAs) linoleic acid and α-linolenic …
Lipid remodeling of adipose tissue in metabolic health and disease
YK Cho, S Lee, J Lee, J Doh, JH Park… - … & Molecular Medicine, 2023 - nature.com
Adipose tissue is a dynamic and metabolically active organ that plays a crucial role in
energy homeostasis and endocrine function. Recent advancements in lipidomics techniques …
energy homeostasis and endocrine function. Recent advancements in lipidomics techniques …
Insulin action in adipocytes, adipose remodeling, and systemic effects
On this 100 th anniversary of the discovery of insulin, we recognize the critical role that
adipocytes, which are exquisitely responsive to insulin, have played in determining the …
adipocytes, which are exquisitely responsive to insulin, have played in determining the …
Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides
K Brejchova, FPW Radner, L Balas… - Proceedings of the …, 2021 - National Acad Sciences
Branched esters of palmitic acid and hydroxy stearic acid are antiinflammatory and
antidiabetic lipokines that belong to a family of fatty acid (FA) esters of hydroxy fatty acids …
antidiabetic lipokines that belong to a family of fatty acid (FA) esters of hydroxy fatty acids …
Branched and linear fatty acid esters of hydroxy fatty acids (FAHFA) relevant to human health
M Riecan, V Paluchova, M Lopes, K Brejchova… - Pharmacology & …, 2022 - Elsevier
Fatty acid esters of hydroxy fatty acids (FAHFAs) represent a complex lipid class that
contains both signaling mediators and structural components of lipid biofilms in humans …
contains both signaling mediators and structural components of lipid biofilms in humans …