Beneficial effects of fecal microbiota transplantation in recurrent Clostridioides difficile infection
Fecal microbiota transplantation (FMT) is highly effective in preventing recurrent
Clostridioides difficile infection (rCDI). However, the mechanisms underpinning its clinical …
Clostridioides difficile infection (rCDI). However, the mechanisms underpinning its clinical …
[HTML][HTML] The role of fecal sulfur metabolome in inflammatory bowel diseases
A Walker, P Schmitt-Kopplin - International journal of medical microbiology, 2021 - Elsevier
Sulfur metabolism and sulfur-containing metabolites play an important role in the human
digestive system, and sulfur compounds and pathways are associated with inflammatory …
digestive system, and sulfur compounds and pathways are associated with inflammatory …
Enterococci enhance Clostridioides difficile pathogenesis
Enteric pathogens are exposed to a dynamic polymicrobial environment in the
gastrointestinal tract. This microbial community has been shown to be important during …
gastrointestinal tract. This microbial community has been shown to be important during …
[HTML][HTML] Bacterial species associated with human inflammatory bowel disease and their pathogenic mechanisms
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal
tract with unknown etiology. The pathogenesis of IBD results from immune responses to …
tract with unknown etiology. The pathogenesis of IBD results from immune responses to …
A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection
Clostridioides difficile infection (CDI) is an urgent public health threat with limited
preventative options. In this work, we developed a messenger RNA (mRNA)–lipid …
preventative options. In this work, we developed a messenger RNA (mRNA)–lipid …
Omics in gut microbiome analysis
Our understanding of the interactions between microbial communities and their niche in the
host gut has improved owing to recent advances in environmental microbial genomics …
host gut has improved owing to recent advances in environmental microbial genomics …
[HTML][HTML] Gut metabolites predict Clostridioides difficile recurrence
JJ Dawkins, JR Allegretti, TE Gibson, E McClure… - Microbiome, 2022 - Springer
Background Clostridioides difficile infection (CDI) is the most common hospital acquired
infection in the USA, with recurrence rates> 15%. Although primary CDI has been …
infection in the USA, with recurrence rates> 15%. Although primary CDI has been …
Dietary fiber-based regulation of bile salt hydrolase activity in the gut microbiota and its relevance to human disease
Complications of short bowel syndrome (SBS) include malabsorption and bacterial
overgrowth, requiring prolonged dependence on parenteral nutrition (PN). We hypothesized …
overgrowth, requiring prolonged dependence on parenteral nutrition (PN). We hypothesized …
[HTML][HTML] Gut microbial metabolome in inflammatory bowel disease: From association to therapeutic perspectives
M Li, L Yang, C Mu, Y Sun, Y Gu, D Chen, T Liu… - Computational and …, 2022 - Elsevier
Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis
(UC), is a set of clinically chronic, relapsing gastrointestinal inflammatory disease and lacks …
(UC), is a set of clinically chronic, relapsing gastrointestinal inflammatory disease and lacks …
[HTML][HTML] Metabolomics as a promising resource identifying potential biomarkers for inflammatory bowel disease
C Bauset, L Gisbert-Ferrándiz… - Journal of Clinical …, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a relapsing chronic disorder of the gastrointestinal tract
characterized by disruption of epithelial barrier function and excessive immune response to …
characterized by disruption of epithelial barrier function and excessive immune response to …