Adeno-associated virus (AAV) vectors are the leading platform for gene delivery for the
treatment of a variety of human diseases. Recent advances in developing clinically …

Chimeric antigen receptor (CAR)-T cell therapy is a progressive new pillar in immune cell
therapy for cancer. It has yielded remarkable clinical responses in patients with B-cell …

Viral vectors provide an efficient means for modification of eukaryotic cells, and their use is
now commonplace in academic laboratories and industry for both research and clinical …

With rapid advances in understanding molecular pathogenesis of human diseases in the era
of genome sciences and systems biology, it is anticipated that increasing numbers of …

Immunotherapy using chimeric antigen receptor-modified T cells has demonstrated high
response rates in patients with B cell malignancies, and chimeric antigen receptor T cell …

Chimeric antigen receptor redirected T cells (CAR-T cells) have achieved inspiring
outcomes in patients with B cell malignancies, and are now being investigated in other …

MicroRNAs (miRNAs) represent a family of short non-coding regulatory RNA molecules that
are produced in a tissue and time-specific manner to orchestrate gene expression post …

The treatment of cancer patients with autologous T cells expressing a chimeric antigen
receptor (CAR) is one of the most promising adoptive cellular therapy approaches …

Influenza A virus is one of the most important zoonotic pathogens that can cause severe
symptoms and has the potential to cause high number of deaths and great economic loss …

Mesoporous silica nanoparticles (MSNs) are a key example of the innovation in material
science to develop nanotechnology-based delivery systems. Biological and pharmaceutical …