Dopamine, immunity, and disease

B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - ASPET
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

[HTML][HTML] Inflammation in Parkinson's disease: mechanisms and therapeutic implications

M Pajares, A I. Rojo, G Manda, L Boscá, A Cuadrado - Cells, 2020 - mdpi.com
Parkinson's disease (PD) is a common neurodegenerative disorder primarily characterized
by the death of dopaminergic neurons that project from the substantia nigra pars compacta …

[HTML][HTML] Critical neurotransmitters in the neuroimmune network

TW Hodo, MTP De Aquino, A Shimamoto… - Frontiers in …, 2020 - frontiersin.org
Immune cells rely on cell-cell communication to specify and fine-tune their responses. They
express an extensive network of cell communication modes, including a vast repertoire of …

Where is dopamine and how do immune cells see it?: dopamine-mediated immune cell function in health and disease

SM Matt, PJ Gaskill - Journal of Neuroimmune Pharmacology, 2020 - Springer
Dopamine is well recognized as a neurotransmitter in the brain, and regulates critical
functions in a variety of peripheral systems. Growing research has also shown that …

[HTML][HTML] Parkinson's disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+ Th1/Th2/T17 and Treg in drug-naive and …

N Kustrimovic, C Comi, L Magistrelli, E Rasini… - Journal of …, 2018 - Springer
Background Parkinson's disease (PD) affects an estimated 7 to 10 million people worldwide,
and only symptomatic treatments are presently available to relieve the consequences of …

[HTML][HTML] The sympathetic nervous response in inflammation

G Pongratz, RH Straub - Arthritis research & therapy, 2014 - Springer
Over the past decades evidence has accumulated clearly demonstrating a pivotal role for
the sympathetic nervous system (SNS) and its neurotransmitters in regulating inflammation …

Neurotransmitters: emerging targets in cancer

SH Jiang, LP Hu, X Wang, J Li, ZG Zhang - Oncogene, 2020 - nature.com
Neurotransmitters are conventionally viewed as nerve-secreted substances that mediate the
stimulatory or inhibitory neuronal functions through binding to their respective receptors. In …

[HTML][HTML] Regulation of natural killer cell activity by glucocorticoids, serotonin, dopamine, and epinephrine

S Capellino, M Claus, C Watzl - Cellular & molecular immunology, 2020 - nature.com
The immune system and the nervous system are highly complex organs composed of
various different cells that must interact with each other for proper function of the system …

[HTML][HTML] Immunomodulatory effects of dopamine in inflammatory diseases

Y Feng, Y Lu - Frontiers in immunology, 2021 - frontiersin.org
Dopamine (DA) receptor, a significant G protein-coupled receptor, is classified into two
families: D1-like (D1 and D5) and D2-like (D2, D3, and D4) receptor families, with further …

The immunoregulatory role of dopamine: an update

C Sarkar, B Basu, D Chakroborty, PS Dasgupta… - Brain, behavior, and …, 2010 - Elsevier
The neurotransmitter dopamine (DA) is an important molecule bridging the nervous and
immune systems. DA through autocrine/paracrine manner modulates the functions of …