(CVD) in individuals with type 1 diabetes mellitus (T1DM), the pathophysiology underlying
the relationship between cardiovascular events, CVD risk factors, and T1DM is not well …

Characterized by a surplus of whole-body adiposity, obesity is strongly associated with the
prognosis of atherosclerosis, a hallmark of coronary artery disease (CAD) and the major …

Obesity is the accumulation of abnormal or excessive fat that may interfere with the
maintenance of an optimal state of health. The excess of macronutrients in the adipose …

Objective Type 2 diabetes and obesity are pro-inflammatory states associated with
increased risk of cardiovascular disease. Canagliflozin, an SGLT2 inhibitor, demonstrated …

The metabolic syndrome is a common metabolic disorder that results from the increasing
prevalence of obesity. The disorder is defined in various ways, but in the near future a new …

There has been much effort recently to define the role of adipocytokines, which are soluble
mediators derived mainly from adipocytes (fat cells), in the interaction between adipose …

Obesity, the most common nutritional disorder in industrialized countries, is associated with
an increased mortality and morbidity of cardiovascular disease (CVD). Obesity is primarily …

Increased albuminuria is associated with obesity and diabetes and is a risk factor for
cardiovascular and renal disease. However, the link between early albuminuria and …

The worldwide epidemic of obesity, fostered by the modern lifestyle characterized by the
lack of physical activity and an energy-dense diet, has contributed to create an …

In a recent report, the worldwide prevalence of childhood obesity was estimated to have
increased by 47% between 1980 and 2013. As a result, substantial concerns have been …