Strategies to reduce the risks of mRNA drug and vaccine toxicity

D Bitounis, E Jacquinet, MA Rogers… - Nature Reviews Drug …, 2024 - nature.com
Abstract mRNA formulated with lipid nanoparticles is a transformative technology that has
enabled the rapid development and administration of billions of coronavirus disease 2019 …

[HTML][HTML] Oxysterols: from redox bench to industry

G Poli, V Leoni, F Biasi, F Canzoneri, D Risso, R Menta - Redox Biology, 2022 - Elsevier
More and more attention is nowadays given to the possible translational application of a
great number of biochemical and biological findings with the involved molecules. This is …

Adverse effect of oxidized cholesterol exposure on colitis is mediated by modulation of gut microbiota

C Yan, SH Huang, HF Ding, E Kwek, JH Liu… - Journal of Hazardous …, 2023 - Elsevier
Both cholesterol and oxidized cholesterol (OXC) are present in human diets. The incidence
of inflammatory bowel diseases (IBDs) is increasing in the world. The present study was to …

Dietary cholesterol oxidation products: Perspectives linking food processing and storage with health implications

Y Liu, X Yang, F Xiao, F Jie, Q Zhang… - … Reviews in Food …, 2022 - Wiley Online Library
Dietary cholesterol oxidation products (COPs) are heterogeneous compounds formed
during the processing and storage of cholesterol‐rich foods, such as seafood, meat, eggs …

Muscle food and human health: A systematic review from the perspective of external and internal oxidation

Z Wang, Z Wu, J Tu, B Xu - Trends in Food Science & Technology, 2023 - Elsevier
Background Muscle food provides a variety of nutrients to maintain the normal activities and
metabolism of the human body. However, a series of studies have revealed a close …

[HTML][HTML] Effect of plasma-activated water (PAW) soaking on the lipid oxidation of sardine (Sardina pilchardus) fillets

M Mozzon, R Foligni, C Mannozzi, F Galdenzi… - Food Research …, 2024 - Elsevier
The efficacy of plasma-activated water (PAW) as a chemical-free and environmentally
friendly preservative has been documented for a variety of foods, but the onset of lipid …

Cholesterol Oxidation Products: Potential Adverse Effect and Prevention of Their Production in Foods

C Deng, M Li, Y Liu, C Yan, Z He… - Journal of Agricultural …, 2023 - ACS Publications
Cholesterol oxidation products (COPs) are a group of substances formed during food
processing. COPs in diet is a health concern because they may affect human health in …

Dietary oxidized cholesterol aggravates chemically induced murine colon inflammation and alters gut microbial ecology

C Yan, E Kwek, HF Ding, Z He, KY Ma… - Journal of Agricultural …, 2022 - ACS Publications
Western diet with a higher intake of fat and cholesterol has been claimed as an intestinal
inflammation trigger. Human diet contains both cholesterol and oxidized cholesterol …

Oxysterols—how much do we know about food occurrence, dietary intake and absorption?

G Garcia-Llatas, D Mercatante, G López-García… - Current Opinion in Food …, 2021 - Elsevier
Highlights•Industrial and household food processing promotes oxysterol formation.•POPs
intake should be monitored due to increasing vegetarian and vegan food trends.•COPs …

A Novel method for the determination of squalene, cholesterol and their oxidation products in food of animal origin by GC-TOF/MS

M Czerwonka, A Białek… - International Journal of …, 2024 - mdpi.com
Cholesterol present in food of animal origin is a precursor of oxysterols (COPs), whose high
intake through diet can be associated with health implications. Evaluation of the content of …