Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment
Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …
cancer treatment, and the research and development of nanoparticles for drug delivery are …
Protein corona: Friend or foe? Co-opting serum proteins for nanoparticle delivery
For systemically delivered nanoparticles to reach target tissues, they must first circulate long
enough to reach the target and extravasate there. A challenge is that the particles end up …
enough to reach the target and extravasate there. A challenge is that the particles end up …
Bacteria‐derived outer‐membrane vesicles hitchhike neutrophils to enhance ischemic stroke therapy
J Pan, Z Wang, X Huang, J Xue, S Zhang… - Advanced …, 2023 - Wiley Online Library
The treatment of reperfusion injury after ischemic stroke remains unsatisfactory since the
blood‐brain barrier (BBB) prevents most neuroprotective agents from entering the brain …
blood‐brain barrier (BBB) prevents most neuroprotective agents from entering the brain …
The protein corona hampers the transcytosis of transferrin-modified nanoparticles through blood–brain barrier and attenuates their targeting ability to brain tumor
W Xiao, Y Wang, H Zhang, Y Liu, R Xie, X He, Y Zhou… - Biomaterials, 2021 - Elsevier
The modification of targeting ligands on nanoparticles (NPs) is anticipated to enhance the
delivery of therapeutics to diseased tissues. However, once exposed to the blood stream …
delivery of therapeutics to diseased tissues. However, once exposed to the blood stream …
[HTML][HTML] Nanomedicine for acute respiratory distress syndrome: the latest application, targeting strategy, and rational design
Q Qiao, X Liu, T Yang, K Cui, L Kong, C Yang… - … Pharmaceutica Sinica B, 2021 - Elsevier
Acute respiratory distress syndrome (ARDS) is characterized by the severe inflammation
and destruction of the lung air–blood barrier, leading to irreversible and substantial …
and destruction of the lung air–blood barrier, leading to irreversible and substantial …
[HTML][HTML] Advanced hitchhiking nanomaterials for biomedical applications
Hitchhiking, a recently developed bio-inspired cargo delivery system, has been harnessed
for diverse applications. By leveraging the interactions between nanoparticles and …
for diverse applications. By leveraging the interactions between nanoparticles and …
Spotlight on the protein corona of liposomes
N Onishchenko, D Tretiakova, E Vodovozova - Acta biomaterialia, 2021 - Elsevier
Although an established drug delivery platform, liposomes have not fulfilled their true
potential. In the body, interactions of liposomes are mediated by the layer of plasma proteins …
potential. In the body, interactions of liposomes are mediated by the layer of plasma proteins …
Nanotechnology reinforced neutrophil-based therapeutic strategies for inflammatory diseases therapy
J Wu, T Ma, M Zhu, T Huang, B Zhang, J Gao, N Lin - Nano Today, 2022 - Elsevier
Misguided attack of immune systems on self-tissue or multifactorial uncontrolled
inflammation is capable of causing inflammatory diseases. Neutrophils play a critical role in …
inflammation is capable of causing inflammatory diseases. Neutrophils play a critical role in …
The advances of neutrophil-derived effective drug delivery systems: a key review of managing tumors and inflammation
H Wang, J Zang, Z Zhao, Q Zhang… - International journal of …, 2021 - Taylor & Francis
The chimeric trait of recruitment by inflammatory signals endows neutrophils with the
functionality of migrating to inflamed tissues, which can be utilized to tailor novel drug …
functionality of migrating to inflamed tissues, which can be utilized to tailor novel drug …
Tailoring the physicochemical properties of nanomaterials for immunomodulation
Immunomodulation is poised to revolutionize the treatment of cancer, autoimmune diseases,
and many other inflammation-related disorders. The immune system in these conditions can …
and many other inflammation-related disorders. The immune system in these conditions can …