The cytoskeleton of a cell controls all the aspects of cell shape changes and motility from its
physiological functions for survival to reproduction to death. The structure and dynamics of …

The cytoskeleton, an intricate network of protein filaments, motor proteins, and cross-linkers,
largely determines the mechanical properties of cells. Among the three filamentous …

Vimentin, an intermediate filament protein primarily recognized for its intracellular role in
maintaining cellular structure, has recently garnered increased attention and emerged as a …

Adsorption kinetics of human vimentin on negatively charged substrates (mica, silica, and
polymer particles) was analyzed using atomic force microscopy (AFM), quartz microbalance …

Intermediate filaments are cytoskeletal proteins that are key regulators of cell mechanics, a
role which is intrinsically tied to their hierarchical structure and their unique ability to …

The intermediate filament protein vimentin constitutes a critical sensor for electrophilic and
oxidative stress. We previously showed that vimentin interacts with zinc, which affects its …

Matrix adaptation reconstructs the architecture of cell, and has important implication in
proper biological functioning. However, how the network of cytoskeleton filament undergoes …

Intermediate filament (IF) proteins assemble into highly flexible filaments that organize into
complex cytoplasmic networks: keratins in all types of epithelia, vimentin in endothelia, and …

Vimentin is a highly charged intermediate filament protein that inherently forms extended
dimeric coiled coils, which serve as the basic building blocks of intermediate filaments …

As with most intermediate filament systems, the hierarchical self-assembly of vimentin into
nonpolar filaments requires no nucleators or energy input. Utilizing a set of live-cell, single …