[HTML][HTML] Molecular topography of an entire nervous system

SR Taylor, G Santpere, A Weinreb, A Barrett, MB Reilly… - Cell, 2021 - cell.com
We have produced gene expression profiles of all 302 neurons of the C. elegans nervous
system that match the single-cell resolution of its anatomy and wiring diagram. Our results …

[HTML][HTML] Building and integrating brain-wide maps of nervous system function in invertebrates

TS Kramer, SW Flavell - Current Opinion in Neurobiology, 2024 - Elsevier
The selection and execution of context-appropriate behaviors is controlled by the integrated
action of neural circuits throughout the brain. However, how activity is coordinated across …

The neuropeptidergic connectome of C. elegans

L Ripoll-Sánchez, J Watteyne, HS Sun, R Fernandez… - Neuron, 2023 - cell.com
Efforts are ongoing to map synaptic wiring diagrams, or connectomes, to understand the
neural basis of brain function. However, chemical synapses represent only one type of …

Understanding neural circuit function through synaptic engineering

I Rabinowitch, DA Colón-Ramos, M Krieg - Nature Reviews …, 2024 - nature.com
Synapses are a key component of neural circuits, facilitating rapid and specific signalling
between neurons. Synaptic engineering—the synthetic insertion of new synaptic …

Single-cell analysis reveals inflammatory interactions driving macular degeneration

M Kuchroo, M DiStasio, E Song, E Calapkulu… - Nature …, 2023 - nature.com
Due to commonalities in pathophysiology, age-related macular degeneration (AMD)
represents a uniquely accessible model to investigate therapies for neurodegenerative …

A multi-scale brain map derived from whole-brain volumetric reconstructions

CA Brittin, SJ Cook, DH Hall, SW Emmons, N Cohen - Nature, 2021 - nature.com
Animal nervous system organization is crucial for all body functions and its disruption can
lead to severe cognitive and behavioural impairment. This organization relies on features …

Multiview confocal super-resolution microscopy

Y Wu, X Han, Y Su, M Glidewell, JS Daniels, J Liu… - Nature, 2021 - nature.com
Confocal microscopy remains a major workhorse in biomedical optical microscopy owing to
its reliability and flexibility in imaging various samples, but suffers from substantial point …

Brain-wide representations of behavior spanning multiple timescales and states in C. elegans

AA Atanas, J Kim, Z Wang, E Bueno, MC Becker… - Cell, 2023 - cell.com
Changes in an animal's behavior and internal state are accompanied by widespread
changes in activity across its brain. However, how neurons across the brain encode …

Dissecting the functional organization of the C. elegans serotonergic system at whole-brain scale

U Dag, I Nwabudike, D Kang, MA Gomes, J Kim… - Cell, 2023 - cell.com
Serotonin influences many aspects of animal behavior. But how serotonin acts on its diverse
receptors across the brain to modulate global activity and behavior is unknown. Here, we …

Impact of mineral resource rents and fin-tech on green growth: Exploring the mediating role of environmental governance in developed economies

C Zeng, R Ma, P Chen - Resources Policy, 2024 - Elsevier
Natural resource abundance is commonly viewed as a positive sign for any nation.
However, even if it aids economic growth, depending too much on a limited supply of natural …