The immunobiology and immunopathology of chlamydial infections

ME Ward - Apmis, 1995 - Wiley Online Library
Chlamydiae are obligate intracellular bacterial pathogens of eukaryotic cells responsible for
a wide variety of important human and animal infections. In humans, chlamydial infections …

Pathogenesis of pelvic inflammatory disease.

L Weström, P Wölner-Hanssen - Genitourinary medicine, 1993 - ncbi.nlm.nih.gov
Our current concept of the pathogenesis of pelvic inflammatory disease (PID) is a synthesis
of information from many sources. The main part is indirectly derived fromepidemiological …

Growth ofChlamydia pneumoniaein cultured human peripheral blood mononuclear cells and induction of a cytokine response

SSE Kaukoranta-Tolvanen, AM Teppo, K Laitinen… - Microbial …, 1996 - Elsevier
In vitroinfection of freshly isolated human peripheral blood mononuclear cells (HPBMC)
withChlamydia pneumoniaewas found to induce a production of tumour necrosis factorα …

Type I Interferon Signaling Exacerbates Chlamydia muridarum Genital Infection in a Murine Model

UM Nagarajan, D Prantner, JD Sikes… - Infection and …, 2008 - Am Soc Microbiol
Type I interferons (IFNs) induced during in vitro chlamydial infection exert bactericidal and
immunomodulatory functions. To determine the precise role of type I IFNs during in vivo …

Focal lymphocytic aggregates in chronic hepatitis C: occurrence, immunohistochemical characterization, and relation to markers of autoimmunity

MA Freni, D Artuso, G Gerken, C Spanti, T Marafioti… - Hepatology, 1995 - Elsevier
Intrahepatic lymphocytic aggregates are observed in chronic hepatitis C as well as in
autoimmune chronic hepatitis. Autoantibodies and autoimmune manifestations may occur in …

Immunopathogenesis of conjunctival scarring in trachoma

AMA El-Asrar, KF Tabbara, SA Al-Kharashi, K Geboes… - Eye, 1998 - nature.com
Purpose Trachoma, a chronic follicular conjunctivitis caused by infection with Chlamydia
trachomatis, is the leading cause of preventable blindness. The blinding complications are …

Chlamydia and chronic arthritis

JD Carter, RD Inman, J Whittum-Hudson… - Annals of …, 2012 - Taylor & Francis
Certain bacterial infections have been demonstrated to be causative of reactive arthritis. The
most common bacterial trigger of reactive arthritis is Chlamydia trachomatis. Chlamydia …

Mechanisms of Chlamydia‐induced disease

ME Ward - Chlamydia: intracellular biology, pathogenesis, and …, 1999 - Wiley Online Library
This chapter discusses the possible role of gamma interferon (IFN‐γ) and heat shock
proteins (Hsps) in the pathogenesis of chlamydial disease. It reviews preliminary evidence …

Interleukin-6 involvement in mesothelioma pathobiology: inhibition by interferon α immunotherapy

H Bielefeldt-Ohmann, AL Marzo, RP Himbeck… - Cancer Immunology …, 1995 - Springer
A role for interleukin-6 (IL-6) in malignant mesothelioma has been suggested by the
clinically presenting symptoms of mesothelioma patients, which include fever, weight loss …

Regulation of chlamydial spreading from the small intestine to the large intestine by IL-22-producing CD4+ T cells

Y Xu, Y Wang, H Winner, H Yang, R He… - Infection and …, 2024 - Am Soc Microbiol
Following an oral inoculation, Chlamydia muridarum descends to the mouse large intestine
for long-lasting colonization. However, a mutant C. muridarum that lacks the plasmid …