[HTML][HTML] The role of oxidative stress in neurodegenerative diseases
Oxidative stress is induced by an imbalanced redox states, involving either excessive
generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. The …
generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. The …
A Guide to the Metabolic Pathways and Function of Metabolites Observed in Human Brain 1H Magnetic Resonance Spectra
CD Rae - Neurochemical research, 2014 - Springer
The current knowledge of the normal biochemistry of compounds that give rise to
resonances in human brain proton magnetic resonance spectra measureable at readily …
resonances in human brain proton magnetic resonance spectra measureable at readily …
Brain glutathione levels–a novel biomarker for mild cognitive impairment and Alzheimer's disease
Background Extant data from in vivo animal models and postmortem studies indicate that
Alzheimer's disease (AD) pathology is associated with reduction of the brain antioxidant …
Alzheimer's disease (AD) pathology is associated with reduction of the brain antioxidant …
Glutathione as a marker for human disease
G Teskey, R Abrahem, R Cao, K Gyurjian… - Advances in clinical …, 2018 - Elsevier
Glutathione (GSH), often referred to as “the master antioxidant,” participates not only in
antioxidant defense systems, but many metabolic processes, and therefore its role cannot be …
antioxidant defense systems, but many metabolic processes, and therefore its role cannot be …
Edited 1H magnetic resonance spectroscopy in vivo: Methods and metabolites
The Proton magnetic resonance (1H‐MRS) spectrum contains information about the
concentration of tissue metabolites within a predefined region of interest (a voxel). The …
concentration of tissue metabolites within a predefined region of interest (a voxel). The …
1H MR Spectroscopy of the Brain: Absolute Quantification of Metabolites1
Hydrogen 1 (1H) magnetic resonance (MR) spectroscopy enables noninvasive in vivo
quantification of metabolite concentrations in the brain. Currently, metabolite concentrations …
quantification of metabolite concentrations in the brain. Currently, metabolite concentrations …
Glutathione in the human brain: Review of its roles and measurement by magnetic resonance spectroscopy
CD Rae, SR Williams - Analytical biochemistry, 2017 - Elsevier
We review the transport, synthesis and catabolism of glutathione in the brain as well as its
compartmentation and biochemistry in different brain cells. The major reactions involving …
compartmentation and biochemistry in different brain cells. The major reactions involving …
MR spectroscopy and spectroscopic imaging of the brain
H Zhu, PB Barker - Magnetic resonance neuroimaging: methods and …, 2011 - Springer
Magnetic resonance spectroscopy (MRS) and the related technique of magnetic resonance
spectroscopic imaging (MRSI) are widely used in both clinical and preclinical research for …
spectroscopic imaging (MRSI) are widely used in both clinical and preclinical research for …
The neurochemical profile quantified by in vivo 1H NMR spectroscopy
Proton NMR spectroscopy is emerging from translational and preclinical neuroscience
research as an important tool for evidence based diagnosis and therapy monitoring. It …
research as an important tool for evidence based diagnosis and therapy monitoring. It …
Brain oxidative stress: detection and mapping of anti-oxidant marker 'Glutathione'in different brain regions of healthy male/female, MCI and Alzheimer patients using …
PK Mandal, M Tripathi, S Sugunan - Biochemical and biophysical research …, 2012 - Elsevier
Glutathione (GSH) serves as an important anti-oxidant in the brain by scavenging harmful
reactive oxygen species that are generated during different molecular processes. The GSH …
reactive oxygen species that are generated during different molecular processes. The GSH …