The health benefits of regular exercise are well established. Nonetheless, the molecular
mechanism (s) responsible for exercise-induced health benefits remain a topic of debate …

The sirtuin system consists of seven highly conserved regulatory enzymes responsible for
metabolism, antioxidant protection, and cell cycle regulation. The great interest in sirtuins is …

The sirtuins form a family of evolutionarily conserved nicotinamide adenine dinucleotide
(NAD)-dependent deacetylases. Seven sirtuins (SIRT1–SIRT7) have been described in …

Sirtuins (Sirts) are implicated in regulating a myriad of biologic functions ranging from cell
growth and metabolism to longevity. Here, we show that nuclear Sirt, Sirt6, and …

Sirtuin 3 (SIRT3) is an NAD+ dependent deacetylase that resides primarily in mitochondria
and functions to maintain mitochondrial homeostasis under stress. SIRT3 expression has …

ABSTRACT CARM1 (coactivator associated arginine methyltransferase 1) has recently
emerged as a powerful regulator of skeletal muscle biology. However, the molecular …

Sirtuin enzymes are a family of highly seven conserved protein deacetylases, namely SIRT1
through SIRT7, whose enzymatic activities require the cofactor nicotinamide adenine …

The acetylation/acylation (ac (et) ylation) of lysine side chains is a dynamic post-translational
modification (PTM) regulating fundamental cellular processes with implications on the …

Increasing evidence suggests that mitochondrial respiratory chain complex I participates in
carcinogenesis and cancer progression by providing energy and maintaining mitochondrial …

This study examined changes in LRP 130 gene and protein expression in response to an
acute bout of sprint‐interval training (SIT) and 6 weeks of SIT in human skeletal muscle. In …