Background Despite significant reductions in mother-to-child HIV-1 transmission risks due to
the advancements and scale-up of antiretroviral therapy (ART), the global burden of HIV-1 …

There have been limited studies linking baseline factors, including the viral load (VL) test,
with virological non-suppression since the introduction of dolutegravir (DTG)-based …

Objectives The aim of this study was to evaluate HIV-1 drug resistance among patients
failing first-line antiretroviral therapy in Ethiopia. Methods A total of 699 adults infected with …

Background Drug resistance mutation testing is a key element for HIV clinical management,
informing effective treatment regimens. However, resistance screening in current clinical …

(1) Background: Efavirenz plasma concentration displays wide between-patient variability
partly due to pharmacogenetic variation and autoinduction. Pediatric data on efavirenz …

Background: Optimal care for children with HIV infection includes timely assessment of
treatment failure. Using HIV viral load to define treatment failure remains a challenge in …

There is limited data on virologic outcome and its correlates among HIV-infected children in
resource-limited settings. We investigated rate and correlates of virologic outcome among …

Background Antiretroviral therapy (ART) was rolled-out in Ethiopia in 2005, but there are no
reports on outcome of ART and human immunodeficiency virus drug resistance (HIVDR) at …

Objectives The predictive efficacy of integrase (IN) strand transfer inhibitors (INSTIs) was
investigated in HIV-infected children born to HIV-infected mothers in Africa. Methods Plasma …

Pediatric human immunodeficiency virus (HIV) care in resource-limited settings remains a
major challenge to achieving global HIV treatment and virologic suppression targets, in part …