Toward rapid,“green”, predictable microwave-assisted synthesis

BA Roberts, CR Strauss - Accounts of Chemical Research, 2005 - ACS Publications
Continuous and batch microwave reactors were constructed for efficient,“green” synthesis
with low-boiling solvents at high temperature in closed vessels. Capabilities for rapid …

A century-old one-pot multicomponent Biginelli reaction products still finds a niche in drug discoveries: Synthesis, mechanistic studies and diverse biological activities …

S Faizan, TF Roohi, RM Raju, Y Sivamani… - Journal of Molecular …, 2023 - Elsevier
One of the largest classes of organic molecules are dihydropyrimidines and its derivatives.
They are widely used in a variety of pharmacological and industrial applications. Their …

Brønsted Base-Catalyzed One-Pot Three-Component Biginelli-Type Reaction: An Efficient Synthesis of 4,5,6-Triaryl-3,4-dihydropyrimidin-2(1H)-one and Mechanistic …

ZL Shen, XP Xu, SJ Ji - The Journal of Organic Chemistry, 2010 - ACS Publications
An efficient one-pot synthesis of 4, 5, 6-triaryl-3, 4-dihydropyrimidin-2 (1 H)-ones via a three-
component Biginelli-type condensation of aldehyde, 2-phenylacetophenone, and …

Montmorillonite K10 catalyzed efficient synthesis of amidoalkyl naphthols under solvent free conditions

S Kantevari, SVN Vuppalapati, L Nagarapu - Catalysis communications, 2007 - Elsevier
An efficient green protocol for the preparation of amidoalkyl naphthols, employing a three-
component one-pot condensation reaction of β-naphthol, aromatic aldehyde, amides or urea …

Synthesis of some tetrahydropyrimidine-5-carboxylates, determination of their metal chelating effects and inhibition profiles against acetylcholinesterase …

A Sujayev, E Garibov, P Taslimi, İ Gulçin… - Journal of enzyme …, 2016 - Taylor & Francis
(Methacryloyloxy) ethyl 6-methyl-2-oxo-4-phenyl-1, 2, 3, 4-tetrahydropyrimidine-5-
carboxylate, is a cyclic urea derivative synthesized from urea, 2-(methacryloyloxy) ethyl …

Past, present and future of the Biginelli reaction: a critical perspective.

JS Sandhu - ARKIVOC: Online Journal of Organic …, 2012 - search.ebscohost.com
This review covers up to 2010 and some available references of 2011 of synthetic advances
in the Biginelli reaction, including recent mechanistic advances, new building blocks, new …

The three‐component Biginelli reaction: a combined experimental and theoretical mechanistic investigation

ROMA De Souza, ET da Penha… - … A European Journal, 2009 - Wiley Online Library
Biginelli reactions have been monitored by direct infusion electrospray ionization mass
spectrometry (ESI‐MS) and key cationic intermediates involved in this three‐component …

A chemical placebo: NaCl as an effective, cheapest, non-acidic and greener catalyst for Biginelli-type 3,4-dihydropyrimidin-2(1H)-ones (-thiones) synthesis

MA Kolosov, VD Orlov, DA Beloborodov… - Molecular diversity, 2009 - Springer
Despite prior reports of several really effective catalytic and non-catalytic approaches
towards Biginelli's 3, 4-dihydropyrimidin-2 (1 H)-ones, an overwhelming number of new …

Facile synthesis of tetrazolo [1, 5-a] pyrimidine with the aid of an effective gallic acid nanomagnetic catalyst

A Maleki, M Niksefat, J Rahimi, S Azadegan - Polyhedron, 2019 - Elsevier
The present work is the first report of nano-Fe 3 O 4@ SiO 2-NH-gallic acid in
multicomponent reactions as a catalyst. One-pot condensation of various aromatic …

Sulfamic acid incorporated HKUST-1: a highly active catalyst and efficient adsorbent

MM Kaid, A Gebreil, SA El-Hakam, AI Ahmed… - RSC …, 2020 - pubs.rsc.org
Herein we introduce an effective approach for incorporating sulfamic acid (SA) into HKUST-
1. The synthesized materials have been characterized using XRD, XPS, BET, FT-IR, SEM …