Peroral Route:  An Opportunity for Protein and Peptide Drug Delivery

A Sood, R Panchagnula - Chemical Reviews, 2001 - ACS Publications
The better understanding of endogenous proteins, peptides, and peptidergic molecules and
their role in various body functions and pathological conditions in last few decades has …

Hydrogels for site-specific oral drug delivery: synthesis and characterization

H Brøndsted, J Kopec̆ek - Biomaterials, 1991 - Elsevier
Novel types of hydrogels based on hydrophilic N-substituted (meth) acrylamides, N-tert-
butylacrylamide and acrylic acid cross-linked with 4, 4′-di (methacryloylamino) …

Hydrogels for oral drug delivery of peptides: Synthesis and characterization

SK Bajpai, J Sonkusley - Journal of applied polymer science, 2002 - Wiley Online Library
In this study hydrogels were synthesized by the copolymerization of acrylamide and itaconic
acid in the presence of poly (N‐vinyl‐2‐pyrrolidone) in an aqueous medium. The …

Insulin stabilization and GI absorption

L Hovgaard, EJ Mack, SW Kim - Journal of controlled release, 1992 - Elsevier
A stabilized insulin formulation based on the concept of physical interaction of the
hydrophobic regions of the insulin molecule with the hydrophobic portion of stabilizing …

Hydrogels for colon-specific oral drug delivery: synthesis and characterization

SK Bajpai, SJ Sonkusley - Journal of Macromolecular Science, Part …, 2001 - Taylor & Francis
Hydrogels have been synthesized by free radical co-polymerization of acrylamide and
maleic acid in the presence of poly (N-vinyl-2-pyrrolidone) in aqueous medium. The …

[PDF][PDF] Hydrogels for colon-specific peptide drug delivery

H Brondsted - 1991 - scholar.archive.org
Novel hydrogels based on hydrophilic N-substituted (meth) acrylamides, N-tert-
butylacrylamide and acrylic acid crosslinked with azoaromatic compounds of varying length …

[引用][C] Enhancement of intestinal peptide absorption

E Touitou - Journal of controlled release, 1992 - Elsevier
The various segments of the intestine differ in physiological characteristics (Table 1)) which
affect the delivery of polypeptides. Intestinal bioavailability of most peptides and proteins is …