HPA axis in the pathomechanism of depression and schizophrenia: new therapeutic strategies based on its participation
J Mikulska, G Juszczyk, M Gawrońska-Grzywacz… - Brain sciences, 2021 - mdpi.com
The hypothalamic-pituitary-adrenal (HPA) axis is involved in the pathophysiology of many
neuropsychiatric disorders. Increased HPA axis activity can be observed during chronic …
neuropsychiatric disorders. Increased HPA axis activity can be observed during chronic …
Neurodevelopmental optimization after early-life adversity: cross-species studies to elucidate sensitive periods and brain mechanisms to inform early intervention
Human brain development is influenced by early-life experiences, particularly during
sensitive periods, with impact on cognitive and emotional outcomes. Understanding how the …
sensitive periods, with impact on cognitive and emotional outcomes. Understanding how the …
[HTML][HTML] A predictable home environment may protect child mental health during the COVID-19 pandemic
Objective Information about the adverse effects of the COVID-19 pandemic on adolescent
and adult mental health is growing, yet the impacts on preschool children are only emerging …
and adult mental health is growing, yet the impacts on preschool children are only emerging …
Childhood unpredictability and the development of exploration
Early in development, the process of exploration helps children gather new information that
fosters learning about the world. Yet, it is unclear how childhood experiences may influence …
fosters learning about the world. Yet, it is unclear how childhood experiences may influence …
Early-life adversity and neurological disease: age-old questions and novel answers
Neurological illnesses, including cognitive impairment, memory decline and dementia, affect
over 50 million people worldwide, imposing a substantial burden on individuals and society …
over 50 million people worldwide, imposing a substantial burden on individuals and society …
Contribution of early‐life unpredictability to neuropsychiatric symptom patterns in adulthood
AD Spadoni, M Vinograd, B Cuccurazzu… - Depression and …, 2022 - Wiley Online Library
Background Recent studies in both human and experimental animals have identified
fragmented and unpredictable parental and environmental signals as a novel source of …
fragmented and unpredictable parental and environmental signals as a novel source of …
What's next? Advances and challenges in understanding how environmental predictability shapes the development of cognitive control
Y Munakata, D Placido… - Current Directions in …, 2023 - journals.sagepub.com
Forming predictions about what will happen next in the world happens early in development,
without instruction, and across species. Some environments support more accurate …
without instruction, and across species. Some environments support more accurate …
Adaptation in the face of adversity: Decrements and enhancements in children's cognitive control behavior following early caregiving instability
Cognitive control is typically described as disrupted following exposure to early caregiving
instability. While much of the work within this field has approached cognitive control broadly …
instability. While much of the work within this field has approached cognitive control broadly …
Early life exposure to unpredictable parental sensory signals shapes cognitive development across three species
Exposure to early life adversity has long term consequences on cognitive function. Most
research has focused on understanding components of early life adversities that contribute …
research has focused on understanding components of early life adversities that contribute …
Neurodevelopmental origins of substance use disorders: Evidence from animal models of early‐life adversity and addiction
Addiction is a chronic relapsing disorder with devastating personal, societal, and economic
consequences. In humans, early‐life adversity (ELA) such as trauma, neglect, and resource …
consequences. In humans, early‐life adversity (ELA) such as trauma, neglect, and resource …