Pain is an unpleasant sensory and emotional experience associated with actual or potential
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …

Complex regional pain syndrome (CRPS) is a chronic pain condition often involving
hyperalgesia and allodynia of the extremities. CRPS is divided into CRPS-I and CRPS-II …

Background Fascial plane blocks (FPBs) target the space between two fasciae, rather than
discrete peripheral nerves. Despite their popularity, their mechanisms of action remain …

Background The objective of this review was to merge current treatment guidelines and best
practice recommendations for management of neuropathic pain into a comprehensive …

Complex regional pain syndrome (CRPS) is a life-altering condition that usually affects the
extremities after a trauma or nerve injury. The physiologic changes that occur as a result of …

Neuropathic pain (NP) is often refractory to pharmacologic and noninterventional treatment.
On behalf of the International Association for the Study of Pain Neuropathic Pain Special …

Pain is a common problem in cancer survivors, especially in the first few years after
treatment. In the longer term, approximately 5% to 10% of survivors have chronic severe …

Background There is currently no strong consensus regarding the optimal management of
complex regional pain syndrome although a multitude of interventions have been described …

It is from the discovery of leptin and the central nervous system as a regulator of bone
remodeling that the presence of autonomic nerves within the skeleton transitioned from a …

Internal medicine is a vast and complicated field that is based on strong scientific and
clinical foundations. Moreover it is rapidly evolving and one needs periodic updating and …