Admixture and clinical phenotypic variation

LH Goetz, L Uribe-Bruce, D Quarless, O Libiger… - Human …, 2014 - karger.com
All human populations exhibit some level of genetic differentiation. This differentiation, or
population stratification, has many interacting sources, including historical migrations …

Free fatty acid G-protein coupled receptor signaling in M1 skewed white adipose tissue macrophages

WA Vieira, H Sadie-Van Gijsen, WF Ferris - Cellular and Molecular Life …, 2016 - Springer
Obesity is associated with the establishment and maintenance of a low grade, chronically
inflamed state in the white adipose tissue (WAT) of the body. The WAT macrophage …

Contribution of genetic ancestry and polygenic risk score in meeting vitamin B12 needs in healthy Brazilian children and adolescents

CA Fuzo, F da Veiga Ued, S Moco, O Cominetti… - Scientific Reports, 2021 - nature.com
Polymorphisms in genes related to the metabolism of vitamin B12 haven't been examined in
a Brazilian population. To (a) determine the correlation between the local genetic ancestry …

Genetic admixture and obesity: recent perspectives and future applications

JR Fernández, KE Pearson, KP Kell… - Human heredity, 2013 - karger.com
The process of the colonization of the New World that occurred centuries ago served as a
natural experiment, creating unique combinations of genetic material in newly formed …

Fatores de risco para doenças cardiovasculares em quilombos contemporâneos do Brasil Central: parâmetros demográficos, socioeconômicos, ancestralidade …

SG Paiva - 2017 - icts.unb.br
O componente étnico-racial e a ancestralidade genética nas pesquisas em saúde estão
entre os temas mais debatidos na ciência, principalmente quando associados a populações …

[PDF][PDF] Impact of obesity and related factors in breast cancer survivorship among Hispanic women

EV Bandera, CC Hong, B Qin - Advancing the science of cancer in …, 2023 - library.oapen.org
Breast cancer is the leading cause of cancer death among US Hispanic women [1]. In
Hispanic women, breast cancer tends to be diagnosed at an earlier age, at a more …

Investigation of associations of European, African, Amerindian genomic ancestries and MC4R, FTO, FAIM2, BDNF loci with obesity-related traits in Rio de Janeiro …

A Scharf, FF Bezerra, VM Zembrzuski… - Anais da Academia …, 2023 - SciELO Brasil
A complex web of causation is involved in adiposity, including environmental, social and
genetic factors. We aimed to investigate associations between genetic factors such as …

Circulating miR‐34a and bone mineral density of Brazilian very‐old adults

OT Nóbrega, GS Morais-Junior, NI Viana… - Journal of Aging …, 2020 - Wiley Online Library
The human aging is marked by several body changes, including in bone mineral density
(BMD). Research shows that microRNAs are important modulators of bone metabolism. The …

Biogeographic ancestry is associated with higher total body adiposity among African-American females: the Boston Area Community Health Survey

SD Goonesekera, SC Fang, RS Piccolo, JC Florez… - PLoS …, 2015 - journals.plos.org
Objectives The prevalence of obesity is disproportionately higher among African-Americans
and Hispanics as compared to whites. We investigated the role of biogeographic ancestry …

Genetic ancestry in relation to the metabolic response to a US versus traditional Mexican diet: a randomized crossover feeding trial among women of Mexican descent

M Santiago-Torres, J De Dieu Tapsoba… - European journal of …, 2017 - nature.com
Results: The genetic ancestral background was 56% IA, 38% European and 6% African.
Women in the highest IA ancestry tertile (> 62%) were shorter in height, less educated and …