In both type 1 and type 2 diabetes, the late diabetic complications in nerve, vascular
endothelium, and kidney arise from chronic elevations of glucose and possibly other …

The relationship between diabetes, insulin and zinc (Zn) is complex with no clear cause and
effect relationships. In Type 1 diabetes there is a lack of insulin production, in Type 2 …

Entrapment of mammalian cells in physical membranes has been practiced since the early
1950s when it was originally introduced as a basic research tool. The method has since …

Neutrophils are crucial innate immune cells and comprise 50–70% of the white blood cell
population under homeostatic conditions. Upon infection and in cancer, blood neutrophil …

OBJECTIVE In diabetes, the persistence of hyperglycemia has been reported to cause
increased production of oxygen free radicals through glucose autooxidation and …

Insulin-dependent diabetes mellitus (IDDM) is a disease that results from autoimmune
destruction of the insulin-producing β-cells in the pancreatic islets of Langerhans. The …

Islet transplantation offers a logical means to treat insulin-dependent diabetes. However, for
reasons poorly understood, the clinical results with islet transplantation have been vastly …

The remarkable difference in success rates between clinical pancreas transplantation and
islet transplantation is poorly understood. Despite the same histocompatibility barrier and …

The effects of a transient exposure to hydrogen peroxide (10 min at 200 μmH 2 O 2) on
pancreatic beta cell signal transduction and insulin secretion have been evaluated. In rat …

The aim of this study was to analyze the effect of the flavonoid silymarin, a free radical
scavenger that prevents lipoperoxidation, on the pancreatic activity of superoxide dismutase …